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7SHE

Cryo-EM structure of human GPR158

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(A, B)
G-protein coupled receptor 158polymer78188251.62UniProt (Q5T848)
Pfam (PF22572)
Pfam (PF00003)
Homo sapiens (human)
2C
(A)
1,2-dioleoyl-sn-glycero-3-phosphoethanolaminenon-polymer744.01Chemie (PEE)
3D
(A)
(2S)-1-{[(S)-hydroxy{[(1s,2R,3R,4R,5S,6S)-2,3,4,5,6-pentahydroxycyclohexyl]oxy}phosphoryl]oxy}-3-(octadecanoyloxy)propan-2-yl (5E,8E,11E,14E)-icosa-5,8,11,14-tetraenoatenon-polymer887.11Chemie (EIJ)
4E, F, G, H, I...
(A, B)
CHOLESTEROLnon-polymer386.722Chemie (CLR)
Sequence modifications
A, B: 1 - 775 (UniProt: Q5T848)
PDBExternal DatabaseDetails
Leu 776-expression tag
Glu 777-expression tag
Val 778-expression tag
Leu 779-expression tag
Phe 780-expression tag
Gln 781-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight176503.3
Non-Polymers*Number of molecules24
Total formula weight10137.5
All*Total formula weight186640.8
*Water molecules are not included.

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PDB entries from 2025-06-18

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