7SGM
Crystal structure of a Fab variant containing a fluorescent noncanonical amino acid with blocked excited state proton transfer and in complex with its antigen, CD40L
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C (A, B, C) | CD40 ligand | polymer | 146 | 15812.8 | 3 | UniProt (P29965) Pfam (PF00229) | Homo sapiens (Human) | CD40-L,T-cell antigen Gp39,TNF-related activation protein,TRAP,Tumor necrosis factor ligand superfamily member 5 |
| 2 | D, F, H (H, K, X) | 5c8* Fab heavy chain | polymer | 226 | 24005.8 | 3 | Homo sapiens | ||
| 3 | E, G, I (L, M, Y) | 5c8* Fab light chain | polymer | 218 | 24013.6 | 3 | Homo sapiens | ||
| 4 | J, M, O (A, B, C) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 3 | Chemie (NAG) | |||
| 5 | K (A) | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL | non-polymer | 122.1 | 1 | Chemie (TRS) | |||
| 6 | BA, CA, L, N, P... (Y, A, B, C, H...) | DI(HYDROXYETHYL)ETHER | non-polymer | 106.1 | 13 | Chemie (PEG) | |||
| 7 | AA, S, X (Y, L, M) | trimethylamine oxide | non-polymer | 75.1 | 3 | Chemie (TMO) | |||
| 8 | DA, EA, FA, GA, HA... (A, B, C, H, L...) | water | water | 18.0 | 1276 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 9 |
| Total formula weight | 191496.7 | |
| Non-Polymers* | Number of molecules | 20 |
| Total formula weight | 2390.7 | |
| All* | Total formula weight | 193887.3 |
