7SF7
LPHN3 (ADGRL3) 7TM domain bound to tethered agonist in complex with G protein heterotrimer
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Isoform 1 of Adhesion G protein-coupled receptor L3 | polymer | 303 | 34313.7 | 1 | UniProt (Q9HAR2-1) Pfam (PF00002) Pfam (PF02354) UniProt (by SIFTS) (Q9HAR2) In PDB | Homo sapiens (Human) | Calcium-independent alpha-latrotoxin receptor 3,CIRL-3,Latrophilin-3,Lectomedin-3 |
| 2 | B | G protein subunit 13 (Gi2-mini-G13 chimera) | polymer | 230 | 26574.4 | 1 | Pfam (PF00503) UniProt (by SIFTS) (Q14344) In PDB | Homo sapiens (Human) | |
| 3 | C | Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 | polymer | 340 | 37416.9 | 1 | UniProt (P62873) Pfam (PF00400) In PDB | Homo sapiens (Human) | Transducin beta chain 1 |
| 4 | D | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 | polymer | 71 | 7861.1 | 1 | UniProt (P59768) Pfam (PF00631) In PDB | Homo sapiens (Human) | G gamma-I |
| 5 | water | water | 18.0 | 3 | Chemie (HOH) |
Sequence modifications
A: 842 - 1138 (UniProt: Q9HAR2-1)
| PDB | External Database | Details |
|---|---|---|
| Leu 1139 | - | expression tag |
| Glu 1140 | - | expression tag |
| Val 1141 | - | expression tag |
| Leu 1142 | - | expression tag |
| Phe 1143 | - | expression tag |
| Gln 1144 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 106166.2 | |
| All* | Total formula weight | 106166.2 |
