7SEG
Crystal structure of the complex of CD16A bound by an anti-CD16A Fab
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C (L, B) | anti-CD16a Fab light chain | polymer | 236 | 25662.6 | 2 | Homo sapiens (human) | ||
| 2 | B, D (H, A) | anti-CD16A Fab heavy chain | polymer | 247 | 26649.0 | 2 | Homo sapiens (human) | ||
| 3 | E, F (D, C) | Low affinity immunoglobulin gamma Fc region receptor III-A | polymer | 180 | 20456.8 | 2 | UniProt (P08637) Pfam (PF13895) | Homo sapiens (Human) | CD16a antigen,Fc-gamma RIII-alpha,Fc-gamma RIII,Fc-gamma RIIIa,FcRIII,FcRIIIa,FcR-10,IgG Fc receptor III-2 |
| 4 | G (E) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 1 | In PDB GlyTouCan (G42666HT) | |||
| 5 | H (L) | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
| 6 | I, J, K (D, C) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 3 | Chemie (NAG) | |||
| 7 | L, M, N, O, P... (L, H, B, A, D...) | water | water | 18.0 | 198 | Chemie (HOH) |
Sequence modifications
D, C: -5 - 172 (UniProt: P08637)
| PDB | External Database | Details |
|---|---|---|
| Ser -3 | Met 18 | conflict |
| Gln 35 | Asn 56 | conflict |
| Gln 71 | Asn 92 | conflict |
| Val 155 | Phe 176 | variant |
| Gln 166 | Asn 187 | conflict |
| Gly 173 | - | expression tag |
| Asn 174 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 145536.8 | |
| Branched | Number of molecules | 1 |
| Total formula weight | 424.4 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 755.7 | |
| All* | Total formula weight | 146716.9 |
