7SD5

Crystallographic structure of neutralizing antibody 10-40 in complex with SARS-CoV-2 spike receptor binding domain

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	Spike protein S1	polymer	239	26898.3	1	UniProt (P0DTC2) Pfam (PF09408) In PDB	Severe acute respiratory syndrome coronavirus 2 (2019-nCoV)
2	H	10-40 Heavy chain	polymer	236	25202.2	1		Homo sapiens (Human)
3	L	10-40 Light chain	polymer	216	23257.5	1		Homo sapiens (Human)
4	B	2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		424.4	1	In PDB GlyTouCan (G42666HT)
5		water	water		18.0	678	Chemie (HOH)

Sequence modifications

A: 319 - 537 (UniProt: P0DTC2)

PDB	External Database	Details
Ala 316	-	expression tag
Pro 317	-	expression tag
Arg 318	-	expression tag
Gly 538	-	expression tag
Ser 539	-	expression tag
Leu 540	-	expression tag
Glu 541	-	expression tag
Val 542	-	expression tag
Leu 543	-	expression tag
Phe 544	-	expression tag
Gln 545	-	expression tag
Gly 546	-	expression tag
Pro 547	-	expression tag
Gly 548	-	expression tag
His 549	-	expression tag
His 550	-	expression tag
His 551	-	expression tag
His 552	-	expression tag
His 553	-	expression tag
His 554	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	3
	Total formula weight	75358.0
Branched	Number of molecules	1
	Total formula weight	424.4
All*	Total formula weight	75782.4

*Water molecules are not included.