7SD5
Crystallographic structure of neutralizing antibody 10-40 in complex with SARS-CoV-2 spike receptor binding domain
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Spike protein S1 | polymer | 239 | 26898.3 | 1 | UniProt (P0DTC2) Pfam (PF09408) | Severe acute respiratory syndrome coronavirus 2 (2019-nCoV) | |
| 2 | B (H) | 10-40 Heavy chain | polymer | 236 | 25202.2 | 1 | Homo sapiens (Human) | ||
| 3 | C (L) | 10-40 Light chain | polymer | 216 | 23257.5 | 1 | Homo sapiens (Human) | ||
| 4 | D (B) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 1 | In PDB GlyTouCan (G42666HT) | |||
| 5 | E, F, G (A, H, L) | water | water | 18.0 | 678 | Chemie (HOH) |
Sequence modifications
A: 319 - 537 (UniProt: P0DTC2)
| PDB | External Database | Details |
|---|---|---|
| Ala 316 | - | expression tag |
| Pro 317 | - | expression tag |
| Arg 318 | - | expression tag |
| Gly 538 | - | expression tag |
| Ser 539 | - | expression tag |
| Leu 540 | - | expression tag |
| Glu 541 | - | expression tag |
| Val 542 | - | expression tag |
| Leu 543 | - | expression tag |
| Phe 544 | - | expression tag |
| Gln 545 | - | expression tag |
| Gly 546 | - | expression tag |
| Pro 547 | - | expression tag |
| Gly 548 | - | expression tag |
| His 549 | - | expression tag |
| His 550 | - | expression tag |
| His 551 | - | expression tag |
| His 552 | - | expression tag |
| His 553 | - | expression tag |
| His 554 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 75358.0 | |
| Branched | Number of molecules | 1 |
| Total formula weight | 424.4 | |
| All* | Total formula weight | 75782.4 |
