7SCD
Ternary complex of fixed-arm Trx-3ost5 (I299E) with 8mer-1 octasaccharide substrate and co-factor product PAP
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Thioredoxin 1,Heparan sulfate glucosamine 3-O-sulfotransferase 5 | polymer | 372 | 42821.4 | 1 | UniProt (P0AA25) UniProt (Q8IZT8) Pfam (PF00085) Pfam (PF00685) In PDB | Escherichia coli | Trx-1,Heparan sulfate D-glucosaminyl 3-O-sulfotransferase 5,3-OST-5,Heparan sulfate 3-O-sulfotransferase 5,h3-OST-5 |
2 | C | 2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-beta-D-glucopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-beta-D-glucopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-beta-D-glucopyranuronic acid | branched | 1510.2 | 1 | In PDB | |||
3 | A | ADENOSINE-3'-5'-DIPHOSPHATE | non-polymer | 427.2 | 1 | Chemie (A3P) | |||
4 | water | water | 18.0 | 8 | Chemie (HOH) |
Sequence modifications
A: 1 - 108 (UniProt: P0AA25)
A: 1086 - 1346 (UniProt: Q8IZT8)
PDB | External Database | Details |
---|---|---|
Ala 109 | - | linker |
Ala 110 | - | linker |
Ala 111 | - | linker |
PDB | External Database | Details |
---|---|---|
Glu 1299 | Ile 299 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 42821.4 | |
Branched | Number of molecules | 1 |
Total formula weight | 1510.2 | |
Non-Polymers* | Number of molecules | 1 |
Total formula weight | 427.2 | |
All* | Total formula weight | 44758.9 |