7SAQ

Cryo-EM structure of TMEM106B fibrils extracted from a FTLD-TDP patient, polymorph 1

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D, E (A, B, C, D, E)	Transmembrane protein 106B	polymer	274	31156.3	5	UniProt (Q9NUM4) Pfam (PF21002) Pfam (PF07092)	Homo sapiens (Human)
2	F, G, H, I, J... (A, B, C, D, E)	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	20	Chemie (NAG)

Contents of the asymmetric unit

Polymers	Number of chains	5
	Total formula weight	155781.6
Non-Polymers*	Number of molecules	20
	Total formula weight	4424.2
All*	Total formula weight	160205.8

*Water molecules are not included.