7S5R
Crystal structure of SARS-CoV-2 receptor binding domain in complex with neutralizing antibodies CV07-287 and COVA1-16
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Spike protein S1 | polymer | 231 | 26095.3 | 1 | UniProt (P0DTC2) Pfam (PF09408) In PDB | Severe acute respiratory syndrome coronavirus 2 (2019-nCoV) | |
| 2 | H | COVA1-16 Heavy chain | polymer | 232 | 25100.1 | 1 | Homo sapiens (human) | ||
| 3 | L | COVA1-16 Light chain | polymer | 214 | 23415.8 | 1 | Homo sapiens (human) | ||
| 4 | B | CV07-287 Heavy chain | polymer | 226 | 24172.2 | 1 | Homo sapiens (human) | ||
| 5 | C | CV07-287 Light chain | polymer | 216 | 23534.0 | 1 | Homo sapiens (human) | ||
| 6 | A, H, B | 1,2-ETHANEDIOL | non-polymer | 62.1 | 8 | Chemie (EDO) | |||
| 7 | A | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 1 | Chemie (NAG) | |||
| 8 | A, H, L, B | SULFATE ION | non-polymer | 96.1 | 10 | Chemie (SO4) | |||
| 9 | water | water | 18.0 | 225 | Chemie (HOH) |
Sequence modifications
A: 319 - 541 (UniProt: P0DTC2)
| PDB | External Database | Details |
|---|---|---|
| Ser 542 | - | expression tag |
| Gly 543 | - | expression tag |
| His 544 | - | expression tag |
| His 545 | - | expression tag |
| His 546 | - | expression tag |
| His 547 | - | expression tag |
| His 548 | - | expression tag |
| His 549 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 5 |
| Total formula weight | 122317.4 | |
| Non-Polymers* | Number of molecules | 19 |
| Total formula weight | 1678.4 | |
| All* | Total formula weight | 123995.8 |
