7S0W

Crystal structure of the T337M variant of human PGM-1

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Phosphoglucomutase-1	polymer	585	64221.8	2	UniProt (P36871) Pfam (PF02878) Pfam (PF02879) Pfam (PF02880)	Homo sapiens (Human)	PGM 1,Glucose phosphomutase 1
2	C, N (A, B)	COBALT (II) ION	non-polymer		58.9	2	Chemie (CO)
3	D, E, F, G, H... (A, B)	SULFATE ION	non-polymer		96.1	13	Chemie (SO4)
4	I (A)	GLYCEROL	non-polymer		92.1	1	Chemie (GOL)
5	S, T (A, B)	water	water		18.0	64	Chemie (HOH)

Sequence modifications

A, B: 1 - 562 (UniProt: P36871)

PDB	External Database	Details
Met -22	-	initiating methionine
His -21	-	expression tag
His -20	-	expression tag
His -19	-	expression tag
His -18	-	expression tag
His -17	-	expression tag
His -16	-	expression tag
Ser -15	-	expression tag
Ser -14	-	expression tag
Gly -13	-	expression tag
Val -12	-	expression tag
Asp -11	-	expression tag
Leu -10	-	expression tag
Gly -9	-	expression tag
Thr -8	-	expression tag
Glu -7	-	expression tag
Asn -6	-	expression tag
Leu -5	-	expression tag
Tyr -4	-	expression tag
Phe -3	-	expression tag
Gln -2	-	expression tag
Ser -1	-	expression tag
Asn 0	-	expression tag
Met 337	Thr 337	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	128443.7
Non-Polymers*	Number of molecules	16
	Total formula weight	1458.8
All*	Total formula weight	129902.4

*Water molecules are not included.