7S0V
The role of an Asp-Asp pair in the structure, function and inhibition of CTX-M Class A Beta-lactamase
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Beta-lactamase | polymer | 263 | 27999.6 | 1 | UniProt (Q9L5C7) | Escherichia coli | |
| 2 | B (A) | 3-(1H-pyrazol-1-yl)-N-[3-(1H-tetrazol-5-yl)phenyl]-5-(trifluoromethyl)benzamide | non-polymer | 399.3 | 1 | Chemie (J1X) | |||
| 3 | C (A) | water | water | 18.0 | 221 | Chemie (HOH) |
Sequence modifications
A: 25 - 290 (UniProt: Q9L5C7)
| PDB | External Database | Details |
|---|---|---|
| Asn 233 | Asp 236 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 27999.6 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 399.3 | |
| All* | Total formula weight | 28398.9 |
