7RY0
human Hsp90_MC domain structure
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Heat shock protein HSP 90-alpha | polymer | 425 | 49563.6 | 2 | UniProt (P07900) Pfam (PF00183) | Homo sapiens (human) | Heat shock 86 kDa,HSP 86,HSP86,Lipopolysaccharide-associated protein 2,LAP-2,LPS-associated protein 2,Renal carcinoma antigen NY-REN-38 |
| 2 | C, D, E (A, B) | DIMETHYL SULFOXIDE | non-polymer | 78.1 | 3 | Chemie (DMS) | |||
| 3 | F, G (B) | GLYCEROL | non-polymer | 92.1 | 2 | Chemie (GOL) | |||
| 4 | H, I (A, B) | water | water | 18.0 | 138 | Chemie (HOH) |
Sequence modifications
A, B: 293 - 714 (UniProt: P07900)
| PDB | External Database | Details |
|---|---|---|
| Gly 290 | - | expression tag |
| His 291 | - | expression tag |
| Met 292 | - | expression tag |
| Ala 320 | Trp 320 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 99127.3 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 418.6 | |
| All* | Total formula weight | 99545.9 |
