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7RUP

Structure of the human GIGYF2-TNRC6A complex

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
GRB10-interacting GYF protein 2polymer738468.61UniProt (Q6Y7W6)
Pfam (PF02213)
Homo sapiens (Human)PERQ amino acid-rich with GYF domain-containing protein 2,Trinucleotide repeat-containing gene 15 protein
2B
(B)
Trinucleotide repeat-containing gene 6A proteinpolymer161461.61UniProt (Q8NDV7)Homo sapiens (Human)CAG repeat protein 26,EMSY interactor protein,GW182 autoantigen,Protein GW1,Glycine-tryptophan protein of 182 kDa
3C
(A)
SULFATE IONnon-polymer96.11Chemie (SO4)
4D, E
(A, B)
waterwater18.096Chemie (HOH)
Sequence modifications
A: 529 - 597 (UniProt: Q6Y7W6)
PDBExternal DatabaseDetails
Gly 525-expression tag
Pro 526-expression tag
Leu 527-expression tag
Glu 528-expression tag
B: 1476 - 1486 (UniProt: Q8NDV7)
PDBExternal DatabaseDetails
Gly 1471-expression tag
Pro 1472-expression tag
Leu 1473-expression tag
Gly 1474-expression tag
Ser 1475-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight9930.3
Non-Polymers*Number of molecules1
Total formula weight96.1
All*Total formula weight10026.3
*Water molecules are not included.

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PDB entries from 2025-12-10

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