7RUH
Bromodomain-containing protein 4 (BRD4) bromodomain 2 (BD2) complexed with XR844
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Bromodomain-containing protein 4 | polymer | 130 | 15212.6 | 1 | UniProt (O60885) Pfam (PF00439) In PDB | Homo sapiens (Human) | Protein HUNK1 |
| 2 | A | N-{1-[1,1-di(pyridin-2-yl)ethyl]-6-(5-{[(2-fluorophenyl)carbamoyl]amino}-1-methyl-6-oxo-1,6-dihydropyridin-3-yl)-1H-indol-4-yl}-2,2,2-trifluoroethane-1-sulfonamide | non-polymer | 719.7 | 1 | Chemie (7QZ) | |||
| 3 | water | water | 18.0 | 63 | Chemie (HOH) |
Sequence modifications
A: 333 - 460 (UniProt: O60885)
| PDB | External Database | Details |
|---|---|---|
| Ser 331 | - | expression tag |
| Met 332 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 15212.6 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 719.7 | |
| All* | Total formula weight | 15932.3 |
