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7RNV

SH2 domain of guanine nucleotide exchange factor Vav2 in complex with an actin peptide with phosphorylated tyrosine 53

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1AGuanine nucleotide exchange factor VAV2polymer11813807.61UniProt (P52735)
Pfam (PF00017)
In PDB
Homo sapiens (Human)VAV-2
2BActin, alpha skeletal musclepolymer91064.01UniProt (P68133)
In PDB
Homo sapiensAlpha-actin-1
3A1,2-ETHANEDIOLnon-polymer62.12Chemie (EDO)
4waterwater18.037Chemie (HOH)
Sequence modifications
A: 665 - 774 (UniProt: P52735)
PDBExternal DatabaseDetails
Gly 660-expression tag
Pro 661-expression tag
Leu 662-expression tag
Gly 663-expression tag
Ser 664-expression tag
Gly 775-expression tag
Ile 776-expression tag
Leu 777-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight14871.6
Non-Polymers*Number of molecules2
Total formula weight124.1
All*Total formula weight14995.7
*Water molecules are not included.

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PDB entries from 2024-06-12

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