7RLJ

Cryo-EM structure of human p97 bound to CB-5083 and ATPgS.

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D, E... (A, B, C, D, E...)	Transitional endoplasmic reticulum ATPase	polymer	755	84543.7	12	UniProt (P55072) Pfam (PF02359) Pfam (PF02933) Pfam (PF00004) Pfam (PF17862)	Homo sapiens (Human)	TER ATPase,15S Mg(2+)-ATPase p97 subunit,Valosin-containing protein,VCP
2	BA, EA, HA, KA, M... (F, L, G, H, A...)	PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER	non-polymer		523.2	12	Chemie (AGS)
3	CA, FA, IA, LA, N... (F, L, G, H, A...)	MAGNESIUM ION	non-polymer		24.3	12	Chemie (MG)
4	AA, DA, GA, JA, MA... (E, F, L, G, H...)	1-[4-(benzylamino)-7,8-dihydro-5H-pyrano[4,3-d]pyrimidin-2-yl]-2-methyl-1H-indole-4-carboxamide	non-polymer		413.5	12	Chemie (JDP)

Contents of the asymmetric unit

Polymers	Number of chains	12
	Total formula weight	1014524.7
Non-Polymers*	Number of molecules	36
	Total formula weight	11532.3
All*	Total formula weight	1026057.0

*Water molecules are not included.