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7RLI

Cryo-EM structure of human p97 bound to CB-5083 and ADP.

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B, C, D, E...
(A, B, C, D, E...)
Transitional endoplasmic reticulum ATPasepolymer82191231.612UniProt (P55072)
Pfam (PF02359)
Pfam (PF02933)
Pfam (PF00004)
Pfam (PF17862)
Homo sapiens (Human)TER ATPase,15S Mg(2+)-ATPase p97 subunit,Valosin-containing protein,VCP
2AA, CA, EA, GA, IA...
(H, I, J, K, L...)
1-[4-(benzylamino)-7,8-dihydro-5H-pyrano[4,3-d]pyrimidin-2-yl]-2-methyl-1H-indole-4-carboxamidenon-polymer413.512Chemie (JDP)
3BA, DA, FA, HA, JA...
(H, I, J, K, L...)
ADENOSINE-5'-DIPHOSPHATEnon-polymer427.212Chemie (ADP)
Sequence modifications
A, B, C, D, E, F, G, H, I, J, K, L: 2 - 806 (UniProt: P55072)
PDBExternal DatabaseDetails
His -14-expression tag
His -13-expression tag
His -12-expression tag
His -11-expression tag
His -10-expression tag
His -9-expression tag
Gly -8-expression tag
Thr -7-expression tag
Ser -6-expression tag
Glu -5-expression tag
Asn -4-expression tag
Leu -3-expression tag
Tyr -2-expression tag
Phe -1-expression tag
Gln 0-expression tag
Gly 1-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains12
Total formula weight1094779.8
Non-Polymers*Number of molecules24
Total formula weight10088.1
All*Total formula weight1104867.9
*Water molecules are not included.

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PDB entries from 2024-11-13

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