7RLI
Cryo-EM structure of human p97 bound to CB-5083 and ADP.
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B, C, D, E... (A, B, C, D, E...) | Transitional endoplasmic reticulum ATPase | polymer | 821 | 91231.6 | 12 | UniProt (P55072) Pfam (PF02359) Pfam (PF02933) Pfam (PF00004) Pfam (PF17862) | Homo sapiens (Human) | TER ATPase,15S Mg(2+)-ATPase p97 subunit,Valosin-containing protein,VCP |
2 | AA, CA, EA, GA, IA... (H, I, J, K, L...) | 1-[4-(benzylamino)-7,8-dihydro-5H-pyrano[4,3-d]pyrimidin-2-yl]-2-methyl-1H-indole-4-carboxamide | non-polymer | 413.5 | 12 | Chemie (JDP) | |||
3 | BA, DA, FA, HA, JA... (H, I, J, K, L...) | ADENOSINE-5'-DIPHOSPHATE | non-polymer | 427.2 | 12 | Chemie (ADP) |
Sequence modifications
A, B, C, D, E, F, G, H, I, J, K, L: 2 - 806 (UniProt: P55072)
PDB | External Database | Details |
---|---|---|
His -14 | - | expression tag |
His -13 | - | expression tag |
His -12 | - | expression tag |
His -11 | - | expression tag |
His -10 | - | expression tag |
His -9 | - | expression tag |
Gly -8 | - | expression tag |
Thr -7 | - | expression tag |
Ser -6 | - | expression tag |
Glu -5 | - | expression tag |
Asn -4 | - | expression tag |
Leu -3 | - | expression tag |
Tyr -2 | - | expression tag |
Phe -1 | - | expression tag |
Gln 0 | - | expression tag |
Gly 1 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 12 |
Total formula weight | 1094779.8 | |
Non-Polymers* | Number of molecules | 24 |
Total formula weight | 10088.1 | |
All* | Total formula weight | 1104867.9 |