7RKI

Griffithsin-S10Y/S42Y/S88Y

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	Griffithsin	polymer	142	15046.4	2	UniProt (P84801) Pfam (PF01419) In PDB	Griffithsia sp. (strain Q66D336) (Red alga)	GRFT
2	A, B	alpha-D-mannopyranose	non-polymer		180.2	3	Chemie (MAN)
3		water	water		18.0	124	Chemie (HOH)

Sequence modifications

A, B: 2 - 121 (UniProt: P84801)

PDB	External Database	Details
Met -20	-	initiating methionine
Gly -19	-	expression tag
Gly -18	-	expression tag
Ser -17	-	expression tag
Ser -16	-	expression tag
His -15	-	expression tag
His -14	-	expression tag
His -13	-	expression tag
His -12	-	expression tag
His -11	-	expression tag
His -10	-	expression tag
Ser -9	-	expression tag
Ser -8	-	expression tag
Gly -7	-	expression tag
Leu -6	-	expression tag
Val -5	-	expression tag
Pro -4	-	expression tag
Arg -3	-	expression tag
Gly -2	-	expression tag
Ser -1	-	expression tag
Gly 0	-	expression tag
Gly 1	-	expression tag
Tyr 10	Ser 10	engineered mutation
Ala 31	Unk 31	variant
Tyr 42	Ser 42	engineered mutation
Tyr 88	Ser 88	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	30092.8
Non-Polymers*	Number of molecules	3
	Total formula weight	540.5
All*	Total formula weight	30633.2

*Water molecules are not included.