7RKF

Structure of CX3CL1-US28-G11iN18-scFv16 in TL-state

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	Guanine nucleotide-binding protein subunit alpha-11	polymer	352	41254.1	1	UniProt (P29992) Pfam (PF00503) In PDB	Homo sapiens (Human)	G alpha-11,G-protein subunit alpha-11,Guanine nucleotide-binding protein G(y) subunit alpha
2	B	Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1	polymer	345	37728.2	1	UniProt (P62873) Pfam (PF00400) In PDB	Homo sapiens (Human)	Transducin beta chain 1
3	C	Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2	polymer	67	7432.6	1	UniProt (P59768) Pfam (PF00631) In PDB	Homo sapiens (Human)	G gamma-I
4	D	Antibody fragment scFv16	polymer	256	27340.5	1		Mus musculus (mouse)
5	L	Fractalkine	polymer	91	10013.5	1	UniProt (P78423) Pfam (PF00048) In PDB	Homo sapiens (Human)	C-X3-C motif chemokine 1,CX3C membrane-anchored chemokine,Neurotactin,Small-inducible cytokine D1
6	R	G-protein coupled receptor homolog US28	polymer	362	42041.1	1	UniProt (P69332) Pfam (PF00001) In PDB	Human cytomegalovirus (HHV-5 Human herpesvirus 5 Human betaherpesvirus 5)	HHRF3
7	A	GUANOSINE-5'-DIPHOSPHATE	non-polymer		443.2	1	Chemie (GDP)
8	L	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	1	Chemie (NAG)

Sequence modifications

A: 19 - 353 (UniProt: P29992)

PDB	External Database	Details
Gly 2	-	expression tag
Cys 3	-	expression tag
Thr 4	-	expression tag
Leu 5	-	expression tag
Ser 6	-	expression tag
Ala 7	-	expression tag
Glu 8	-	expression tag
Asp 9	-	expression tag
Lys 10	-	expression tag
Ala 11	-	expression tag
Ala 12	-	expression tag
Val 13	-	expression tag
Glu 14	-	expression tag
Arg 15	-	expression tag
Ser 16	-	expression tag
Lys 17	-	expression tag
Met 18	-	expression tag

B: 2 - 340 (UniProt: P62873)

PDB	External Database	Details
Gly -4	-	expression tag
Pro -3	-	expression tag
Gly -2	-	expression tag
Ser -1	-	expression tag
Ser 0	-	expression tag
Gly 1	-	expression tag

L: 1 - 77 (UniProt: P78423)

PDB	External Database	Details
Ser 78	-	expression tag
Gly 79	-	expression tag
Ser 80	-	expression tag
Gly 81	-	expression tag
Ser 82	-	expression tag
Ala 83	-	expression tag
Ala 84	-	expression tag
Ala 85	-	expression tag
Leu 86	-	expression tag
Glu 87	-	expression tag
Val 88	-	expression tag
Leu 89	-	expression tag
Phe 90	-	expression tag
Gln 91	-	expression tag

R: 1 - 354 (UniProt: P69332)

PDB	External Database	Details
Asp -7	-	expression tag
Tyr -6	-	expression tag
Lys -5	-	expression tag
Asp -4	-	expression tag
Asp -3	-	expression tag
Asp -2	-	expression tag
Asp -1	-	expression tag
Ala 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	6
	Total formula weight	165809.9
Non-Polymers*	Number of molecules	2
	Total formula weight	664.4
All*	Total formula weight	166474.3

*Water molecules are not included.