7RKF
Structure of CX3CL1-US28-G11iN18-scFv16 in TL-state
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Guanine nucleotide-binding protein subunit alpha-11 | polymer | 352 | 41254.1 | 1 | UniProt (P29992) Pfam (PF00503) | Homo sapiens (Human) | G alpha-11,G-protein subunit alpha-11,Guanine nucleotide-binding protein G(y) subunit alpha |
| 2 | B (B) | Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 | polymer | 345 | 37728.2 | 1 | UniProt (P62873) Pfam (PF00400) | Homo sapiens (Human) | Transducin beta chain 1 |
| 3 | C (C) | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 | polymer | 67 | 7432.6 | 1 | UniProt (P59768) Pfam (PF00631) | Homo sapiens (Human) | G gamma-I |
| 4 | D (D) | Antibody fragment scFv16 | polymer | 256 | 27340.5 | 1 | Mus musculus (mouse) | ||
| 5 | E (L) | Fractalkine | polymer | 91 | 10013.5 | 1 | UniProt (P78423) Pfam (PF00048) | Homo sapiens (Human) | C-X3-C motif chemokine 1,CX3C membrane-anchored chemokine,Neurotactin,Small-inducible cytokine D1 |
| 6 | F (R) | G-protein coupled receptor homolog US28 | polymer | 362 | 42041.1 | 1 | UniProt (P69332) Pfam (PF00001) | Human cytomegalovirus (HHV-5 Human herpesvirus 5 Human betaherpesvirus 5) | HHRF3 |
| 7 | G (A) | GUANOSINE-5'-DIPHOSPHATE | non-polymer | 443.2 | 1 | Chemie (GDP) | |||
| 8 | H (L) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 1 | Chemie (NAG) |
Sequence modifications
A: 19 - 353 (UniProt: P29992)
B: 2 - 340 (UniProt: P62873)
L: 1 - 77 (UniProt: P78423)
R: 1 - 354 (UniProt: P69332)
| PDB | External Database | Details |
|---|---|---|
| Gly 2 | - | expression tag |
| Cys 3 | - | expression tag |
| Thr 4 | - | expression tag |
| Leu 5 | - | expression tag |
| Ser 6 | - | expression tag |
| Ala 7 | - | expression tag |
| Glu 8 | - | expression tag |
| Asp 9 | - | expression tag |
| Lys 10 | - | expression tag |
| Ala 11 | - | expression tag |
| Ala 12 | - | expression tag |
| Val 13 | - | expression tag |
| Glu 14 | - | expression tag |
| Arg 15 | - | expression tag |
| Ser 16 | - | expression tag |
| Lys 17 | - | expression tag |
| Met 18 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Gly -4 | - | expression tag |
| Pro -3 | - | expression tag |
| Gly -2 | - | expression tag |
| Ser -1 | - | expression tag |
| Ser 0 | - | expression tag |
| Gly 1 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Ser 78 | - | expression tag |
| Gly 79 | - | expression tag |
| Ser 80 | - | expression tag |
| Gly 81 | - | expression tag |
| Ser 82 | - | expression tag |
| Ala 83 | - | expression tag |
| Ala 84 | - | expression tag |
| Ala 85 | - | expression tag |
| Leu 86 | - | expression tag |
| Glu 87 | - | expression tag |
| Val 88 | - | expression tag |
| Leu 89 | - | expression tag |
| Phe 90 | - | expression tag |
| Gln 91 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Asp -7 | - | expression tag |
| Tyr -6 | - | expression tag |
| Lys -5 | - | expression tag |
| Asp -4 | - | expression tag |
| Asp -3 | - | expression tag |
| Asp -2 | - | expression tag |
| Asp -1 | - | expression tag |
| Ala 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 165809.9 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 664.4 | |
| All* | Total formula weight | 166474.3 |
