7RKF
Structure of CX3CL1-US28-G11iN18-scFv16 in TL-state
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Guanine nucleotide-binding protein subunit alpha-11 | polymer | 352 | 41254.1 | 1 | UniProt (P29992) Pfam (PF00503) | Homo sapiens (Human) | G alpha-11,G-protein subunit alpha-11,Guanine nucleotide-binding protein G(y) subunit alpha |
| 2 | B (B) | Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 | polymer | 345 | 37728.2 | 1 | UniProt (P62873) Pfam (PF25391) | Homo sapiens (Human) | Transducin beta chain 1 |
| 3 | C (C) | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 | polymer | 67 | 7432.6 | 1 | UniProt (P59768) Pfam (PF00631) | Homo sapiens (Human) | G gamma-I |
| 4 | D (D) | Antibody fragment scFv16 | polymer | 256 | 27340.5 | 1 | Mus musculus (mouse) | ||
| 5 | E (L) | Fractalkine | polymer | 91 | 10013.5 | 1 | UniProt (P78423) Pfam (PF00048) | Homo sapiens (Human) | C-X3-C motif chemokine 1,CX3C membrane-anchored chemokine,Neurotactin,Small-inducible cytokine D1 |
| 6 | F (R) | G-protein coupled receptor homolog US28 | polymer | 362 | 42041.1 | 1 | UniProt (P69332) | Human cytomegalovirus (HHV-5 Human herpesvirus 5 Human betaherpesvirus 5) | HHRF3 |
| 7 | G (A) | GUANOSINE-5'-DIPHOSPHATE | non-polymer | 443.2 | 1 | Chemie (GDP) PubChem (136073927) PubChem (135398619) PubChem (135402030) PubChem (135431654) PubChem (135566337) PubChem (135760556) PubChem (136026707) PubChem (136053418) PubChem (136663964) PubChem (136664748) PubChem (136759848) PubChem (136759849) PubChem (136759850) PubChem (136836636) PubChem (136847074) PubChem (172898537) | |||
| 8 | H (L) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 1 | Chemie (NAG) |
Sequence modifications
A: 19 - 353 (UniProt: P29992)
B: 2 - 340 (UniProt: P62873)
L: 1 - 77 (UniProt: P78423)
R: 1 - 354 (UniProt: P69332)
| PDB | External Database | Details |
|---|---|---|
| Gly 2 | - | expression tag |
| Cys 3 | - | expression tag |
| Thr 4 | - | expression tag |
| Leu 5 | - | expression tag |
| Ser 6 | - | expression tag |
| Ala 7 | - | expression tag |
| Glu 8 | - | expression tag |
| Asp 9 | - | expression tag |
| Lys 10 | - | expression tag |
| Ala 11 | - | expression tag |
| Ala 12 | - | expression tag |
| Val 13 | - | expression tag |
| Glu 14 | - | expression tag |
| Arg 15 | - | expression tag |
| Ser 16 | - | expression tag |
| Lys 17 | - | expression tag |
| Met 18 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Gly -4 | - | expression tag |
| Pro -3 | - | expression tag |
| Gly -2 | - | expression tag |
| Ser -1 | - | expression tag |
| Ser 0 | - | expression tag |
| Gly 1 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Ser 78 | - | expression tag |
| Gly 79 | - | expression tag |
| Ser 80 | - | expression tag |
| Gly 81 | - | expression tag |
| Ser 82 | - | expression tag |
| Ala 83 | - | expression tag |
| Ala 84 | - | expression tag |
| Ala 85 | - | expression tag |
| Leu 86 | - | expression tag |
| Glu 87 | - | expression tag |
| Val 88 | - | expression tag |
| Leu 89 | - | expression tag |
| Phe 90 | - | expression tag |
| Gln 91 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Asp -7 | - | expression tag |
| Tyr -6 | - | expression tag |
| Lys -5 | - | expression tag |
| Asp -4 | - | expression tag |
| Asp -3 | - | expression tag |
| Asp -2 | - | expression tag |
| Asp -1 | - | expression tag |
| Ala 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 165809.9 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 664.4 | |
| All* | Total formula weight | 166474.3 |
