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7RKF

Structure of CX3CL1-US28-G11iN18-scFv16 in TL-state

Functional Information from GO Data
ChainGOidnamespacecontents
A0001501biological_processskeletal system development
A0001508biological_processaction potential
A0001664molecular_functionG protein-coupled receptor binding
A0001750cellular_componentphotoreceptor outer segment
A0003924molecular_functionGTPase activity
A0003925molecular_functionG protein activity
A0005515molecular_functionprotein binding
A0005525molecular_functionGTP binding
A0005737cellular_componentcytoplasm
A0005765cellular_componentlysosomal membrane
A0005834cellular_componentheterotrimeric G-protein complex
A0005886cellular_componentplasma membrane
A0007165biological_processsignal transduction
A0007186biological_processG protein-coupled receptor signaling pathway
A0007188biological_processadenylate cyclase-modulating G protein-coupled receptor signaling pathway
A0007200biological_processphospholipase C-activating G protein-coupled receptor signaling pathway
A0007207biological_processphospholipase C-activating G protein-coupled acetylcholine receptor signaling pathway
A0007213biological_processG protein-coupled acetylcholine receptor signaling pathway
A0007507biological_processheart development
A0007603biological_processphototransduction, visible light
A0008217biological_processregulation of blood pressure
A0009649biological_processentrainment of circadian clock
A0016020cellular_componentmembrane
A0019001molecular_functionguanyl nucleotide binding
A0030234molecular_functionenzyme regulator activity
A0031683molecular_functionG-protein beta/gamma-subunit complex binding
A0032024biological_processpositive regulation of insulin secretion
A0045202cellular_componentsynapse
A0045634biological_processregulation of melanocyte differentiation
A0046872molecular_functionmetal ion binding
A0048066biological_processdevelopmental pigmentation
A0060158biological_processphospholipase C-activating dopamine receptor signaling pathway
A0070062cellular_componentextracellular exosome
A0071467biological_processcellular response to pH
A0086100biological_processendothelin receptor signaling pathway
A0099105biological_procession channel modulating, G protein-coupled receptor signaling pathway
A1904888biological_processcranial skeletal system development
A1990806biological_processligand-gated ion channel signaling pathway
B0001750cellular_componentphotoreceptor outer segment
B0003924molecular_functionGTPase activity
B0005515molecular_functionprotein binding
B0005737cellular_componentcytoplasm
B0005765cellular_componentlysosomal membrane
B0005829cellular_componentcytosol
B0005834cellular_componentheterotrimeric G-protein complex
B0005886cellular_componentplasma membrane
B0007165biological_processsignal transduction
B0007186biological_processG protein-coupled receptor signaling pathway
B0007191biological_processadenylate cyclase-activating dopamine receptor signaling pathway
B0007200biological_processphospholipase C-activating G protein-coupled receptor signaling pathway
B0007213biological_processG protein-coupled acetylcholine receptor signaling pathway
B0007265biological_processRas protein signal transduction
B0008283biological_processcell population proliferation
B0016020cellular_componentmembrane
B0030159molecular_functionsignaling receptor complex adaptor activity
B0044877molecular_functionprotein-containing complex binding
B0045202cellular_componentsynapse
B0050909biological_processsensory perception of taste
B0051020molecular_functionGTPase binding
B0060041biological_processretina development in camera-type eye
B0070062cellular_componentextracellular exosome
B0071380biological_processcellular response to prostaglandin E stimulus
B0071870biological_processcellular response to catecholamine stimulus
B0097381cellular_componentphotoreceptor disc membrane
B1903561cellular_componentextracellular vesicle
C0005515molecular_functionprotein binding
C0005834cellular_componentheterotrimeric G-protein complex
C0005886cellular_componentplasma membrane
C0007165biological_processsignal transduction
C0007186biological_processG protein-coupled receptor signaling pathway
C0007191biological_processadenylate cyclase-activating dopamine receptor signaling pathway
C0016020cellular_componentmembrane
C0031681molecular_functionG-protein beta-subunit binding
C0048144biological_processfibroblast proliferation
C0070062cellular_componentextracellular exosome
C0071380biological_processcellular response to prostaglandin E stimulus
C0071870biological_processcellular response to catecholamine stimulus
L0005576cellular_componentextracellular region
L0006955biological_processimmune response
L0008009molecular_functionchemokine activity
R0004930molecular_functionG protein-coupled receptor activity
R0004950molecular_functionchemokine receptor activity
R0005515molecular_functionprotein binding
R0006935biological_processchemotaxis
R0006955biological_processimmune response
R0007186biological_processG protein-coupled receptor signaling pathway
R0007204biological_processpositive regulation of cytosolic calcium ion concentration
R0009897cellular_componentexternal side of plasma membrane
R0016020cellular_componentmembrane
R0016493molecular_functionC-C chemokine receptor activity
R0019049biological_processvirus-mediated perturbation of host defense response
R0019722biological_processcalcium-mediated signaling
R0019957molecular_functionC-C chemokine binding
R0020002cellular_componenthost cell plasma membrane
R0044864biological_processpositive regulation by virus of host cell division
R0060326biological_processcell chemotaxis
R0070098biological_processchemokine-mediated signaling pathway
Functional Information from PROSITE/UniProt
site_idPS00237
Number of Residues17
DetailsG_PROTEIN_RECEP_F1_1 G-protein coupled receptors family 1 signature. ASLcFITEIALDRYYaI
ChainResidueDetails
RALA117-ILE133

site_idPS00678
Number of Residues15
DetailsWD_REPEATS_1 Trp-Asp (WD) repeats signature. LVSAsqDgKLIIWDS
ChainResidueDetails
BLEU70-SER84
BILE157-ILE171
BLEU285-ALA299

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues85
DetailsTOPO_DOM: Extracellular => ECO:0000255
ChainResidueDetails
RMET1-LEU37
RGLN91-SER101
RTHR167-SER183
RVAL250-LEU273

site_idSWS_FT_FI2
Number of Residues20
DetailsTRANSMEM: Helical; Name=1 => ECO:0000255
ChainResidueDetails
RPHE38-ILE58
ALEU174
ATHR180
AASN268
AALA325

site_idSWS_FT_FI3
Number of Residues114
DetailsTOPO_DOM: Cytoplasmic => ECO:0000255
ChainResidueDetails
RTHR59-ASP69
RTHR123-CYS145
RSER205-ARG228
RGLY295-PRO354

site_idSWS_FT_FI4
Number of Residues20
DetailsTRANSMEM: Helical; Name=2 => ECO:0000255
ChainResidueDetails
RVAL70-MET90

site_idSWS_FT_FI5
Number of Residues20
DetailsTRANSMEM: Helical; Name=3 => ECO:0000255
ChainResidueDetails
RVAL102-ILE122

site_idSWS_FT_FI6
Number of Residues20
DetailsTRANSMEM: Helical; Name=4 => ECO:0000255
ChainResidueDetails
RLEU146-VAL166

site_idSWS_FT_FI7
Number of Residues20
DetailsTRANSMEM: Helical; Name=5 => ECO:0000255
ChainResidueDetails
RTYR184-ILE204

site_idSWS_FT_FI8
Number of Residues20
DetailsTRANSMEM: Helical; Name=6 => ECO:0000255
ChainResidueDetails
RVAL229-PHE249

site_idSWS_FT_FI9
Number of Residues20
DetailsTRANSMEM: Helical; Name=7 => ECO:0000255
ChainResidueDetails
RILE274-VAL294

site_idSWS_FT_FI10
Number of Residues1
DetailsCARBOHYD: N-linked (GlcNAc...) asparagine; by host => ECO:0000255
ChainResidueDetails
RASN30

222926

PDB entries from 2024-07-24

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