7RIE

Plasmodium falciparum M17 in complex with inhibitor MIPS2571

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D, E... (A, B, C, D, E...)	M17 leucyl aminopeptidase	polymer	527	58577.8	12	UniProt (Q8IL11) Pfam (PF00883)	Plasmodium falciparum
2	BB, EA, GB, IA, LB... (H, D, I, E, J...)	CARBONATE ION	non-polymer		60.0	12	Chemie (CO3)
3	CB, DB, FA, GA, HB... (H, D, I, E, J...)	ZINC ION	non-polymer		65.4	24	Chemie (ZN)
4	AC, BA, CA, JB, NA... (L, C, I, E, J...)	PENTAETHYLENE GLYCOL	non-polymer		238.3	9	Chemie (1PE)
5	AB, BC, DA, FB, HA... (G, L, C, H, D...)	N-{(1R)-2-(hydroxyamino)-1-[4'-(hydroxymethyl)[1,1'-biphenyl]-4-yl]-2-oxoethyl}-2,2-dimethylpropanamide	non-polymer		356.4	12	Chemie (5IF)
6	AA, EB, LA, MA, SA... (C, H, E, F, K...)	SULFATE ION	non-polymer		96.1	11	Chemie (SO4)
7	CC, DC, EC, FC, GC... (A, B, C, D, E...)	water	water		18.0	1527	Chemie (HOH)

Sequence modifications

A, B, C, D, E, F, G, H, I, J, K, L: 85 - 605 (UniProt: Q8IL11)

PDB	External Database	Details
Gln 152	Asn 152	conflict
Gln 515	Asn 515	conflict
Gln 546	Asn 546	conflict
His 606	-	expression tag
His 607	-	expression tag
His 608	-	expression tag
His 609	-	expression tag
His 610	-	expression tag
His 611	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	12
	Total formula weight	702933.3
Non-Polymers*	Number of molecules	68
	Total formula weight	9768.1
All*	Total formula weight	712701.4

*Water molecules are not included.