7RI1
Crystal structure of anti-HIV llama VHH antibody J3 in complex with HIV-1 C1086 gp120
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Glycoprotein 120 | polymer | 382 | 42324.7 | 1 | UniProt (R4GRV3) Pfam (PF00516) UniProt (by SIFTS) (C6G099) In PDB | Human immunodeficiency virus 1 | |
| 2 | B | Lamma VHH antibody J3 | polymer | 130 | 14489.2 | 1 | Lama glama | ||
| 3 | A | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 7 | Chemie (NAG) | |||
| 4 | A, B | SULFATE ION | non-polymer | 96.1 | 5 | Chemie (SO4) | |||
| 5 | water | water | 18.0 | 134 | Chemie (HOH) |
Sequence modifications
A: 44 - 492 (UniProt: R4GRV3)
| PDB | External Database | Details |
|---|---|---|
| Asp 20 | - | expression tag |
| Ile 21 | - | expression tag |
| Ala 22 | - | expression tag |
| Thr 23 | - | expression tag |
| Met 24 | - | expression tag |
| Tyr 25 | - | expression tag |
| Ser 26 | - | expression tag |
| Met 27 | - | expression tag |
| Gln 28 | - | expression tag |
| Leu 29 | - | expression tag |
| Ala 30 | - | expression tag |
| Ser 31 | - | expression tag |
| Cys 32 | - | expression tag |
| Val 33 | - | expression tag |
| Thr 34 | - | expression tag |
| Leu 35 | - | expression tag |
| Thr 36 | - | expression tag |
| Leu 37 | - | expression tag |
| Val 38 | - | expression tag |
| Leu 39 | - | expression tag |
| Leu 40 | - | expression tag |
| Val 41 | - | expression tag |
| Asn 42 | - | expression tag |
| Ser 43 | - | expression tag |
| Lys 63 | Arg 20 | conflict |
| Val 85 | Ala 42 | conflict |
| Ala 87 | Gly 44 | conflict |
| Glu 102 | Asp 59 | conflict |
| Glu 114 | Gln 71 | conflict |
| Ala 200 | Thr 84 | conflict |
| Ile 201 | Val 85 | conflict |
| Leu 215 | Ile 99 | conflict |
| Phe 223 | Tyr 107 | conflict |
| Lys 231 | Glu 115 | conflict |
| Asn 234 | Glu 118 | conflict |
| Arg 240 | Asn 124 | conflict |
| Glu 267 | Lys 151 | conflict |
| Ile 271 | Val 155 | conflict |
| Asn 279 | Asp 163 | conflict |
| Asn 289 | Lys 173 | conflict |
| Asn 293 | Glu 177 | conflict |
| Asn 300 | Gly 184 | conflict |
| Asn 325 | Asp 193 | conflict |
| Ile 326 | Thr 194 | conflict |
| Asn 334 | Ser 202 | conflict |
| Ser 336 | Glu 204 | conflict |
| Asn 340 | Lys 208 | conflict |
| Gly 346 | Ser 214 | conflict |
| Glu 347 | Lys 215 | conflict |
| Glu 348 | Ile 216 | conflict |
| Ala 350 | Gln 218 | conflict |
| Lys 351 | Glu 219 | conflict |
| Ser 356 | Asn 223 | conflict |
| Thr 358 | Ala 225 | conflict |
| Ser 364 | His 231 | conflict |
| Ser 388 | Thr 255 | conflict |
| Asp 389 | Lys 256 | conflict |
| Arg 396 | - | insertion |
| Gly 398 | Ser 264 | conflict |
| Tyr 403 | Ala 266 | conflict |
| His 405 | Ser 268 | conflict |
| Arg 408 | Ser 271 | conflict |
| Ser 409 | Val 272 | conflict |
| Gly 412 | Thr 275 | conflict |
| Gln 417 | Pro 280 | conflict |
| Lys 419 | Arg 282 | conflict |
| Ile 424 | Val 287 | conflict |
| Glu 429 | Gly 292 | conflict |
| Ile 434 | Met 297 | conflict |
| Glu 440 | Lys 303 | conflict |
| Glu 442 | Asn 305 | conflict |
| Asn 446 | Lys 309 | conflict |
| Asn 448 | Ile 311 | conflict |
| Leu 455 | Thr 318 | conflict |
| Gln 459 | - | insertion |
| Ser 459 | - | insertion |
| Glu 459 | Asp 324 | conflict |
| Thr 459 | Asp 325 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 56813.9 | |
| Non-Polymers* | Number of molecules | 12 |
| Total formula weight | 2028.8 | |
| All* | Total formula weight | 58842.7 |
