7RHR

Cryo-EM structure of Xenopus Patched-1 in nanodisc

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Patched-1	polymer	1205	134622.4	1	UniProt (Q98SW6) Pfam (PF12349) Pfam (PF02460)	Xenopus calcaratus
2	B (B)	2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		424.4	1	In PDB GlyTouCan (G42666HT)
3	C, D, G (A)	CHOLESTEROL	non-polymer		386.7	3	Chemie (CLR)
4	E, F (A)	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	2	Chemie (NAG)

Sequence modifications

A: 1 - 1178 (UniProt: Q98SW6)

PDB	External Database	Details
Ser 1179	-	expression tag
Ser 1180	-	expression tag
Ser 1181	-	expression tag
Pro 1182	-	expression tag
Ala 1183	-	expression tag
Ala 1184	-	expression tag
Ala 1185	-	expression tag
His 1186	-	expression tag
His 1187	-	expression tag
His 1188	-	expression tag
His 1189	-	expression tag
His 1190	-	expression tag
His 1191	-	expression tag
His 1192	-	expression tag
His 1193	-	expression tag
Glu 1194	-	expression tag
Asp 1195	-	expression tag
Gln 1196	-	expression tag
Val 1197	-	expression tag
Asp 1198	-	expression tag
Pro 1199	-	expression tag
Arg 1200	-	expression tag
Leu 1201	-	expression tag
Ile 1202	-	expression tag
Asp 1203	-	expression tag
Gly 1204	-	expression tag
Lys 1205	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	134622.4
Branched	Number of molecules	1
	Total formula weight	424.4
Non-Polymers*	Number of molecules	5
	Total formula weight	1602.4
All*	Total formula weight	136649.2

*Water molecules are not included.