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SummaryStructural detailsExperimental detailsFunctional detailsSequence NeighborHistoryDownloads

7RHR

Cryo-EM structure of Xenopus Patched-1 in nanodisc

Functional Information from GO Data
ChainGOidnamespacecontents
A0008158molecular_functionhedgehog receptor activity
A0016020cellular_componentmembrane
Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues18
DetailsTransmembrane: {"description":"Helical; Name=TM1","evidences":[{"source":"PubMed","id":"35231446","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"7RHQ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7RHR","evidenceCode":"ECO:0007744"}]}
ChainResidueDetails
site_idSWS_FT_FI2
Number of Residues611
DetailsTopological domain: {"description":"Extracellular","evidences":[{"source":"PubMed","id":"35231446","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"7RHQ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7RHR","evidenceCode":"ECO:0007744"}]}
ChainResidueDetails
site_idSWS_FT_FI3
Number of Residues18
DetailsTransmembrane: {"description":"Helical; Name=TM2","evidences":[{"source":"PubMed","id":"35231446","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"7RHQ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7RHR","evidenceCode":"ECO:0007744"}]}
ChainResidueDetails
site_idSWS_FT_FI4
Number of Residues48
DetailsTopological domain: {"description":"Cytoplasmic","evidences":[{"source":"PubMed","id":"35231446","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"7RHQ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7RHR","evidenceCode":"ECO:0007744"}]}
ChainResidueDetails
site_idSWS_FT_FI5
Number of Residues25
DetailsTransmembrane: {"description":"Helical; Name=TM3","evidences":[{"source":"PubMed","id":"35231446","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"7RHQ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7RHR","evidenceCode":"ECO:0007744"}]}
ChainResidueDetails
site_idSWS_FT_FI6
Number of Residues19
DetailsTransmembrane: {"description":"Helical; Name=TM4","evidences":[{"source":"PubMed","id":"35231446","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"7RHQ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7RHR","evidenceCode":"ECO:0007744"}]}
ChainResidueDetails
site_idSWS_FT_FI7
Number of Residues20
DetailsTransmembrane: {"description":"Helical; Name=TM5","evidences":[{"source":"PubMed","id":"35231446","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"7RHQ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7RHR","evidenceCode":"ECO:0007744"}]}
ChainResidueDetails
site_idSWS_FT_FI8
Number of Residues23
DetailsTransmembrane: {"description":"Helical; Name=TM6","evidences":[{"source":"PubMed","id":"35231446","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"7RHQ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7RHR","evidenceCode":"ECO:0007744"}]}
ChainResidueDetails
site_idSWS_FT_FI9
Number of Residues21
DetailsTransmembrane: {"description":"Helical; Name=TM7","evidences":[{"source":"PubMed","id":"35231446","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"7RHQ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7RHR","evidenceCode":"ECO:0007744"}]}
ChainResidueDetails
site_idSWS_FT_FI10
Number of Residues20
DetailsTransmembrane: {"description":"Helical; Name=TM8","evidences":[{"source":"PubMed","id":"35231446","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"7RHQ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7RHR","evidenceCode":"ECO:0007744"}]}
ChainResidueDetails
site_idSWS_FT_FI11
Number of Residues21
DetailsTransmembrane: {"description":"Helical; Name=TM9","evidences":[{"source":"PubMed","id":"35231446","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"7RHQ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7RHR","evidenceCode":"ECO:0007744"}]}
ChainResidueDetails
site_idSWS_FT_FI12
Number of Residues19
DetailsTransmembrane: {"description":"Helical; Name=TM10","evidences":[{"source":"PubMed","id":"35231446","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"7RHQ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7RHR","evidenceCode":"ECO:0007744"}]}
ChainResidueDetails
site_idSWS_FT_FI13
Number of Residues20
DetailsTransmembrane: {"description":"Helical; Name=TM11","evidences":[{"source":"PubMed","id":"35231446","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"7RHQ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7RHR","evidenceCode":"ECO:0007744"}]}
ChainResidueDetails
site_idSWS_FT_FI14
Number of Residues25
DetailsTransmembrane: {"description":"Helical; Name=TM12","evidences":[{"source":"PubMed","id":"35231446","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"7RHQ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7RHR","evidenceCode":"ECO:0007744"}]}
ChainResidueDetails
site_idSWS_FT_FI15
Number of Residues160
DetailsDomain: {"description":"SSD","evidences":[{"source":"PROSITE-ProRule","id":"PRU00199","evidenceCode":"ECO:0000255"}]}
ChainResidueDetails
site_idSWS_FT_FI16
Number of Residues319
DetailsRegion: {"description":"Extracellular domain 1 (ECD1)","evidences":[{"source":"PubMed","id":"35231446","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"7RHQ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7RHR","evidenceCode":"ECO:0007744"}]}
ChainResidueDetails
site_idSWS_FT_FI17
Number of Residues256
DetailsRegion: {"description":"Extracellular domain 2 (ECD2)","evidences":[{"source":"PubMed","id":"35231446","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"7RHQ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7RHR","evidenceCode":"ECO:0007744"}]}
ChainResidueDetails
site_idSWS_FT_FI18
Number of Residues1
DetailsGlycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"source":"PubMed","id":"35231446","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"7RHR","evidenceCode":"ECO:0007744"}]}
ChainResidueDetails
site_idSWS_FT_FI19
Number of Residues1
DetailsGlycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"source":"PubMed","id":"35231446","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"7RHQ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7RHR","evidenceCode":"ECO:0007744"}]}
ChainResidueDetails
site_idSWS_FT_FI20
Number of Residues1
DetailsGlycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"source":"PubMed","id":"35231446","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"7RHQ","evidenceCode":"ECO:0007744"}]}
ChainResidueDetails

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PDB entries from 2026-06-17

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