7RH7
Mycobacterial CIII2CIV2 supercomplex, Telacebec (Q203) bound
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, T (W, c) | LpqE protein | polymer | 159 | 16412.9 | 2 | UniProt (I7GFE1) UniProt (by SIFTS) (A0R562) | Mycolicibacterium smegmatis MC2 155 | |
| 2 | B, L (Q, K) | Cytochrome aa3 subunit 2 | polymer | 312 | 35201.0 | 2 | UniProt (I7GD63) Pfam (PF00116) UniProt (by SIFTS) (A0R057) | Mycolicibacterium smegmatis MC2 155 | |
| 3 | C, M (R, L) | Cytochrome c oxidase subunit 1 | polymer | 552 | 61733.2 | 2 | Mycolicibacterium smegmatis MC2 155 | ||
| 4 | D, N (S, X) | Cytochrome aa3 subunit 3 | polymer | 203 | 22196.9 | 2 | UniProt (A0R049) Pfam (PF00510) | Mycolicibacterium smegmatis MC2 155 | Probable cytochrome c oxidase subunit 3 |
| 5 | E, O (T, Z) | Cytochrome c oxidase polypeptide 4 | polymer | 139 | 15177.4 | 2 | UniProt (I7FPH7) Pfam (PF12270) UniProt (by SIFTS) (A0R056) | Mycolicibacterium smegmatis MC2 155 | Cytochrome aa3 subunit 4,Cytochrome c oxidase polypeptide IV |
| 6 | F, P (U, a) | Cytochrome c oxidase subunit CtaJ | polymer | 79 | 8365.5 | 2 | UniProt (I7FQK8) UniProt (by SIFTS) (A0R1B6) | Mycolicibacterium smegmatis MC2 155 | |
| 7 | G, Q (V, b) | Uncharacterized protein MSMEG_4692/MSMEI_4575 | polymer | 145 | 14808.7 | 2 | UniProt (A0R1B5) Pfam (PF17174) | Mycolicibacterium smegmatis MC2 155 | |
| 8 | H, R (P, J) | Conserved transmembrane protein | polymer | 100 | 11329.9 | 2 | UniProt (A0QVH4) Pfam (PF10939) | Mycolicibacterium smegmatis MC2 155 | |
| 9 | I, S (G, D) | Superoxide dismutase [Cu-Zn] | polymer | 216 | 21221.9 | 2 | UniProt (I7G2H6) Pfam (PF00080) UniProt (by SIFTS) (A0QQQ1) | Mycolicibacterium smegmatis MC2 155 | |
| 10 | J, U (O, I) | Cytochrome bc1 complex cytochrome c subunit | polymer | 223 | 23184.0 | 2 | UniProt (I7FPH1) Pfam (PF00034) Pfam (PF13442) | Mycolicibacterium smegmatis MC2 155 | |
| 11 | K, V (E, F) | Cytochrome bc1 complex cytochrome b subunit | polymer | 535 | 59110.8 | 2 | UniProt (I7FGS8) Pfam (PF13631) UniProt (by SIFTS) (A0R052) | Mycolicibacterium smegmatis MC2 155 | Cytochrome bc1 reductase complex subunit QcrB |
| 12 | W, X (Y, M) | Cytochrome bc1 complex Rieske iron-sulfur subunit | polymer | 382 | 42210.5 | 2 | UniProt (I7GD61) Pfam (PF19297) Pfam (PF00355) | Mycolicibacterium smegmatis MC2 155 | Cytochrome bc1 reductase complex subunit QcrA |
| 13 | NA, OB, RB, Y (G, D, c, W) | (2S)-1-(hexadecanoyloxy)propan-2-yl (10S)-10-methyloctadecanoate | non-polymer | 595.0 | 4 | Chemie (9XX) | |||
| 14 | OA, PB, QB, Z (G, D, c, W) | PALMITIC ACID | non-polymer | 256.4 | 4 | Chemie (PLM) | |||
| 15 | AA, BA, BB, CA, CB... (Q, K, R, L) | COPPER (II) ION | non-polymer | 63.5 | 6 | Chemie (CU) | |||
| 16 | DA, EA, EB, FB (R, L) | HEME-A | non-polymer | 852.8 | 4 | Chemie (HEA) | |||
| 17 | AC, BC, CC, FA, HA... (F, R, S, L, X...) | CARDIOLIPIN | non-polymer | 1464.0 | 16 | Chemie (CDL) | |||
| 18 | GA, GB, IB, LA (S, L, X, P) | (2R)-3-(((2-aminoethoxy)(hydroxy)phosphoryl)oxy)-2-(palmitoyloxy)propyl (E)-octadec-9-enoate | non-polymer | 718.0 | 4 | Chemie (9Y0) | |||
| 19 | JA, LB, VA, WA, YB... (T, Z, E, F) | MENAQUINONE-9 | non-polymer | 785.2 | 6 | Chemie (MQ9) | |||
| 20 | PA, QA, SB, TB (O, I) | HEME C | non-polymer | 618.5 | 4 | Chemie (HEC) | |||
| 21 | AB, DC, FC, GC, IC... (E, F, Y, M, O...) | (2R)-2-(hexadecanoyloxy)-3-{[(S)-hydroxy{[(1R,2R,3R,4R,5R,6S)-2,3,4,5,6-pentahydroxycyclohexyl]oxy}phosphoryl]oxy}propyl (9S)-9-methyloctadecanoate | non-polymer | 853.1 | 8 | Chemie (9YF) | |||
| 22 | SA, TA, VB, WB (E, F) | PROTOPORPHYRIN IX CONTAINING FE | non-polymer | 616.5 | 4 | Chemie (HEM) | |||
| 23 | UA, XB (E, F) | 6-chloranyl-2-ethyl-N-[[4-[4-[4-(trifluoromethyloxy)phenyl]piperidin-1-yl]phenyl]methyl]imidazo[1,2-a]pyridine-3-carboxamide | non-polymer | 557.0 | 2 | Chemie (HUU) | |||
| 24 | EC, HC (Y, M) | FE2/S2 (INORGANIC) CLUSTER | non-polymer | 175.8 | 2 | Chemie (FES) |
Sequence modifications
P, J: 18 - 100 (UniProt: A0QVH4)
| PDB | External Database | Details |
|---|---|---|
| Met 1 | - | initiating methionine |
| Ser 2 | - | expression tag |
| Ser 3 | - | expression tag |
| Thr 4 | - | expression tag |
| Gln 5 | - | expression tag |
| Asp 6 | - | expression tag |
| Arg 7 | - | expression tag |
| Ser 8 | - | expression tag |
| Gln 9 | - | expression tag |
| Leu 10 | - | expression tag |
| Asp 11 | - | expression tag |
| Pro 12 | - | expression tag |
| Glu 13 | - | expression tag |
| Glu 14 | - | expression tag |
| Gln 15 | - | expression tag |
| Pro 16 | - | expression tag |
| Val 17 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 24 |
| Total formula weight | 661905.4 | |
| Non-Polymers* | Number of molecules | 64 |
| Total formula weight | 51436.9 | |
| All* | Total formula weight | 713342.3 |
