7RH7

Mycobacterial CIII2CIV2 supercomplex, Telacebec (Q203) bound

Functional Information from GO Data

Chain	GOid	namespace	contents
a	0016020	cellular_component	membrane
D	0004784	molecular_function	superoxide dismutase activity
D	0005507	molecular_function	copper ion binding
D	0005886	cellular_component	plasma membrane
D	0006801	biological_process	superoxide metabolic process
D	0016491	molecular_function	oxidoreductase activity
D	0019430	biological_process	removal of superoxide radicals
D	0046872	molecular_function	metal ion binding
E	0008121	molecular_function	ubiquinol-cytochrome-c reductase activity
E	0009055	molecular_function	electron transfer activity
E	0016020	cellular_component	membrane
E	0016491	molecular_function	oxidoreductase activity
E	0022904	biological_process	respiratory electron transport chain
E	1902600	biological_process	proton transmembrane transport
F	0008121	molecular_function	ubiquinol-cytochrome-c reductase activity
F	0009055	molecular_function	electron transfer activity
F	0016020	cellular_component	membrane
F	0016491	molecular_function	oxidoreductase activity
F	0022904	biological_process	respiratory electron transport chain
F	1902600	biological_process	proton transmembrane transport
G	0004784	molecular_function	superoxide dismutase activity
G	0005507	molecular_function	copper ion binding
G	0005886	cellular_component	plasma membrane
G	0006801	biological_process	superoxide metabolic process
G	0016491	molecular_function	oxidoreductase activity
G	0019430	biological_process	removal of superoxide radicals
G	0046872	molecular_function	metal ion binding
I	0009055	molecular_function	electron transfer activity
I	0020037	molecular_function	heme binding
J	0016020	cellular_component	membrane
K	0004129	molecular_function	cytochrome-c oxidase activity
K	0005507	molecular_function	copper ion binding
K	0016020	cellular_component	membrane
K	0016491	molecular_function	oxidoreductase activity
K	0046872	molecular_function	metal ion binding
K	1902600	biological_process	proton transmembrane transport
L	0004129	molecular_function	cytochrome-c oxidase activity
L	0009060	biological_process	aerobic respiration
L	0015990	biological_process	electron transport coupled proton transport
L	0016020	cellular_component	membrane
L	0020037	molecular_function	heme binding
M	0005886	cellular_component	plasma membrane
M	0046872	molecular_function	metal ion binding
M	0051537	molecular_function	2 iron, 2 sulfur cluster binding
M	0070469	cellular_component	respirasome
O	0009055	molecular_function	electron transfer activity
O	0020037	molecular_function	heme binding
P	0016020	cellular_component	membrane
Q	0004129	molecular_function	cytochrome-c oxidase activity
Q	0005507	molecular_function	copper ion binding
Q	0016020	cellular_component	membrane
Q	0016491	molecular_function	oxidoreductase activity
Q	0046872	molecular_function	metal ion binding
Q	1902600	biological_process	proton transmembrane transport
R	0004129	molecular_function	cytochrome-c oxidase activity
R	0009060	biological_process	aerobic respiration
R	0015990	biological_process	electron transport coupled proton transport
R	0016020	cellular_component	membrane
R	0020037	molecular_function	heme binding
S	0004129	molecular_function	cytochrome-c oxidase activity
S	0005886	cellular_component	plasma membrane
S	0009055	molecular_function	electron transfer activity
S	0016020	cellular_component	membrane
S	0016491	molecular_function	oxidoreductase activity
S	0019646	biological_process	aerobic electron transport chain
S	0022904	biological_process	respiratory electron transport chain
S	1902600	biological_process	proton transmembrane transport
T	0004129	molecular_function	cytochrome-c oxidase activity
T	0005886	cellular_component	plasma membrane
T	0016020	cellular_component	membrane
T	0016491	molecular_function	oxidoreductase activity
T	0022900	biological_process	electron transport chain
T	1902600	biological_process	proton transmembrane transport
U	0016020	cellular_component	membrane
X	0004129	molecular_function	cytochrome-c oxidase activity
X	0005886	cellular_component	plasma membrane
X	0009055	molecular_function	electron transfer activity
X	0016020	cellular_component	membrane
X	0016491	molecular_function	oxidoreductase activity
X	0019646	biological_process	aerobic electron transport chain
X	0022904	biological_process	respiratory electron transport chain
X	1902600	biological_process	proton transmembrane transport
Y	0005886	cellular_component	plasma membrane
Y	0046872	molecular_function	metal ion binding
Y	0051537	molecular_function	2 iron, 2 sulfur cluster binding
Y	0070469	cellular_component	respirasome
Z	0004129	molecular_function	cytochrome-c oxidase activity
Z	0005886	cellular_component	plasma membrane
Z	0016020	cellular_component	membrane
Z	0016491	molecular_function	oxidoreductase activity
Z	0022900	biological_process	electron transport chain
Z	1902600	biological_process	proton transmembrane transport

Functional Information from PROSITE/UniProt

site_id	PS00077
Number of Residues	55
Details	COX1_CUB Heme-copper oxidase catalytic subunit, copper B binding region signature. WFFGHPeVyiialpffgivseifpvfsrkpifgyttliyatlaiaalsvavwa..HH

Chain	Residue	Details
R	TRP260-HIS314

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site_id	PS00078
Number of Residues	55
Details	COX2 CO II and nitrous oxide reductase dinuclear copper centers signature. ViHgfwvpeflfkrdvlpepkannsdnvfqvseiqqtgafvgrCtemCgtfHamM

Chain	Residue	Details
Q	VAL230-MET284

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site_id	PS00332
Number of Residues	12
Details	SOD_CU_ZN_2 Copper/Zinc superoxide dismutase signature 2. GDAGsRvACgvI

Chain	Residue	Details
G	GLY222-ILE233

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	4
Details	CROSSLNK: Isoglutamyl lysine isopeptide (Lys-Gln) (interchain with Q-Cter in protein Pup) => ECO:0000269|PubMed:20094657

Chain	Residue	Details
V	LYS115
b	LYS115

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