7RFB

Crystal structure of broadly neutralizing antibody mAb1198 in complex with Hepatitis C virus envelope glycoprotein E2 ectodomain

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, E (A, H)	mAb1198 Heavy Chain	polymer	237	25090.1	2		Homo sapiens (Human)
2	B, F (B, L)	mAb1198 Light Chain	polymer	220	23915.8	2		Homo sapiens (Human)
3	C, D (C, D)	envelope glycoprotein E2	polymer	262	28946.5	2	UniProt (A0A2P0NE26) Pfam (PF01560)	Hepacivirus C
4	G, H, K (E, F, J)	alpha-D-mannopyranose-(1-6)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		748.7	3	In PDB GlyTouCan (G22573RC)
5	I, J, L (G, I, K)	alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		910.8	3	In PDB GlyTouCan (G22768VO)
6	M, N, O, P, Q... (C, D)	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	6	Chemie (NAG)

Contents of the asymmetric unit

Polymers	Number of chains	6
	Total formula weight	155904.7
Branched	Number of molecules	6
	Total formula weight	4978.5
Non-Polymers*	Number of molecules	6
	Total formula weight	1327.2
All*	Total formula weight	162210.4

*Water molecules are not included.