7RBQ
Co-crystal structure of human PRMT9 in complex with MT556 inhibitor
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Protein arginine N-methyltransferase 9 | polymer | 719 | 80429.2 | 1 | UniProt (Q6P2P2) Pfam (PF06325) Pfam (PF22528) | Homo sapiens (Human) | Protein arginine N-methyltransferase 10 |
| 2 | B (A) | 7-[5-S-(4-{[(4-ethylpyridin-3-yl)methyl]amino}butyl)-5-thio-beta-D-ribofuranosyl]-7H-pyrrolo[2,3-d]pyrimidin-4-amine | non-polymer | 472.6 | 1 | Chemie (44T) | |||
| 3 | C (A) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 1 | Chemie (EDO) | |||
| 4 | D, E, F, G, H (A) | UNKNOWN ATOM OR ION | non-polymer | 5 | Chemie (UNX) | ||||
| 5 | I (A) | water | water | 18.0 | 65 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 80429.2 | |
| Non-Polymers* | Number of molecules | 7 |
| Total formula weight | 534.7 | |
| All* | Total formula weight | 80963.9 |
