7R71
Crystal Structure of the UbArk2C-UbcH5b~Ub complex
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Ubiquitin,E3 ubiquitin-protein ligase RNF165 | polymer | 183 | 20337.1 | 1 | UniProt (P0CG48) UniProt (Q6ZSG1) Pfam (PF00240) Pfam (PF13639) In PDB | Homo sapiens (Human) | Ark2C fused to Ubiquitin |
2 | D | Ubiquitin | polymer | 76 | 8576.8 | 1 | UniProt (P0CG48) Pfam (PF00240) In PDB | Homo sapiens (Human) | |
3 | C | Ubiquitin-conjugating enzyme E2 D2 | polymer | 152 | 17214.6 | 1 | UniProt (P62837) Pfam (PF00179) In PDB | Homo sapiens (Human) | (E3-independent) E2 ubiquitin-conjugating enzyme D2,E2 ubiquitin-conjugating enzyme D2,Ubiquitin carrier protein D2,Ubiquitin-conjugating enzyme E2(17)KB 2,Ubiquitin-conjugating enzyme E2-17 kDa 2,Ubiquitin-protein ligase D2,p53-regulated ubiquitin-conjugating enzyme 1 |
4 | A | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) |
Sequence modifications
A: 1 - 76 (UniProt: P0CG48)
A: 255 - 346 (UniProt: Q6ZSG1)
C: 1 - 147 (UniProt: P62837)
PDB | External Database | Details |
---|---|---|
Gly -4 | - | expression tag |
Pro -3 | - | expression tag |
Leu -2 | - | expression tag |
Gly -1 | - | expression tag |
Ser 0 | - | expression tag |
Gly 77 | - | linker |
Glu 78 | - | linker |
Ser 79 | - | linker |
Gly 80 | - | linker |
Ser 81 | - | linker |
Gly 82 | - | linker |
Gly 83 | - | linker |
Ser 84 | - | linker |
Gly 85 | - | linker |
Ser 86 | - | linker |
C: 1 - 147 (UniProt: P62837)
PDB | External Database | Details |
---|---|---|
Gly -4 | - | expression tag |
Pro -3 | - | expression tag |
Leu -2 | - | expression tag |
Gly -1 | - | expression tag |
Ser 0 | - | expression tag |
Ser 21 | Cys 21 | engineered mutation |
Arg 22 | Ser 22 | engineered mutation |
Lys 85 | Cys 85 | engineered mutation |
Ser 107 | Cys 107 | engineered mutation |
Ser 111 | Cys 111 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 3 |
Total formula weight | 46128.6 | |
Non-Polymers* | Number of molecules | 2 |
Total formula weight | 130.8 | |
All* | Total formula weight | 46259.4 |