7R6G
Crystal structure of DfrA5 dihydrofolate reductase in complex with TRIMETHOPRIM and NADPH
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Dihydrofolate reductase type 5 | polymer | 157 | 17547.0 | 2 | UniProt (P11731) Pfam (PF00186) | Escherichia coli | Dihydrofolate reductase type V |
| 2 | C, F (A, B) | TRIMETHOPRIM | non-polymer | 290.3 | 2 | Chemie (TOP) | |||
| 3 | D, G (A, B) | NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | non-polymer | 745.4 | 2 | Chemie (NDP) | |||
| 4 | E (A) | SULFATE ION | non-polymer | 96.1 | 1 | Chemie (SO4) | |||
| 5 | H, I (A, B) | water | water | 18.0 | 12 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 35094.0 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 2167.5 | |
| All* | Total formula weight | 37261.5 |
