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7R61

BTK in complex with 25A

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Tyrosine-protein kinase BTKpolymer27031541.21UniProt (Q06187)
Pfam (PF07714)
Homo sapiens (Human)Agammaglobulinemia tyrosine kinase,ATK,B-cell progenitor kinase,BPK,Bruton tyrosine kinase
2B
(A)
5-{(3S)-1-[(Z)-iminomethyl]piperidin-3-yl}-2-(4-phenoxyphenoxy)pyridine-3-carboxamidenon-polymer416.51Chemie (2IJ)
3C, D
(A)
DIMETHYL SULFOXIDEnon-polymer78.12Chemie (DMS)
4E
(A)
waterwater18.0105Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight31541.2
Non-Polymers*Number of molecules3
Total formula weight572.7
All*Total formula weight32114.0
*Water molecules are not included.

237735

PDB entries from 2025-06-18

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