7R3Y
The crystal structure of the V426L variant of Pol2CORE in complex with DNA and an incoming nucleotide
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | DNA polymerase epsilon catalytic subunit | polymer | 1186 | 136725.2 | 2 | UniProt (A0A7I9C3S1) Pfam (PF03104) Pfam (PF22634) UniProt (by SIFTS) (P21951) In PDB | Saccharomyces cerevisiae (baker's yeast) | |
2 | P, C | DNA Primer | polymer | 11 | 3293.2 | 2 | synthetic construct | ||
3 | T | DNA Template | polymer | 16 | 4905.2 | 1 | synthetic construct | ||
4 | D | DNA Template | polymer | 16 | 4889.2 | 1 | synthetic construct | ||
5 | A, B | 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE | non-polymer | 491.2 | 2 | Chemie (DTP) | |||
6 | A, B | CALCIUM ION | non-polymer | 40.1 | 4 | Chemie (CA) | |||
7 | water | water | 18.0 | 13 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 1186 (UniProt: A0A7I9C3S1)
PDB | External Database | Details |
---|---|---|
Leu 426 | Val 426 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 6 |
Total formula weight | 289831.1 | |
Non-Polymers* | Number of molecules | 6 |
Total formula weight | 1142.7 | |
All* | Total formula weight | 290973.8 |