7R3X
The crystal structure of the L439V variant of Pol2CORE in complex with DNA and an incoming nucleotide
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | DNA polymerase epsilon catalytic subunit A | polymer | 1185 | 136596.0 | 1 | UniProt (P21951) Pfam (PF03104) Pfam (PF22634) | Saccharomyces cerevisiae (baker's yeast) | 3'-5' exodeoxyribonuclease,DNA polymerase II subunit A |
| 2 | B (P) | DNA Primer | polymer | 11 | 3293.2 | 1 | synthetic construct | ||
| 3 | C (T) | DNA Template | polymer | 16 | 4889.2 | 1 | synthetic construct | ||
| 4 | D (A) | 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE | non-polymer | 491.2 | 1 | Chemie (DTP) | |||
| 5 | E, F (A) | CALCIUM ION | non-polymer | 40.1 | 2 | Chemie (CA) | |||
| 6 | G (A) | ACETATE ION | non-polymer | 59.0 | 1 | Chemie (ACT) | |||
| 7 | H, I, J (A, P, T) | water | water | 18.0 | 96 | Chemie (HOH) |
Sequence modifications
A: 1 - 1185 (UniProt: P21951)
| PDB | External Database | Details |
|---|---|---|
| Val 439 | Leu 439 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 144778.4 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 630.4 | |
| All* | Total formula weight | 145408.7 |
