7R39

Crystal structure of S-adenosyl-L-homocysteine hydrolase from Sulfolobus acidocaldarius in complex with adenosine

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D, E... (A, B, C, D, E...)	Adenosylhomocysteinase	polymer	438	48699.7	8	UniProt (Q4JAZ7) Pfam (PF05221) Pfam (PF00670)	Sulfolobus acidocaldarius	S-adenosyl-L-homocysteine hydrolase,AdoHcyase
2	I, K, M, O, Q... (A, B, C, D, E...)	NICOTINAMIDE-ADENINE-DINUCLEOTIDE	non-polymer		663.4	8	Chemie (NAD)
3	J, L, N, P, R... (A, B, C, D, E...)	ADENOSINE	non-polymer		267.2	8	Chemie (ADN)
4	AA, BA, CA, DA, EA... (C, D, E, F, G...)	water	water		18.0	284	Chemie (HOH)

Sequence modifications

A, B, C, D, E, F, G, H: 1 - 415 (UniProt: Q4JAZ7)

PDB	External Database	Details
Met -22	-	initiating methionine
Gly -21	-	expression tag
Ser -20	-	expression tag
Ser -19	-	expression tag
His -18	-	expression tag
His -17	-	expression tag
His -16	-	expression tag
His -15	-	expression tag
His -14	-	expression tag
His -13	-	expression tag
Ser -12	-	expression tag
Ser -11	-	expression tag
Gly -10	-	expression tag
Leu -9	-	expression tag
Val -8	-	expression tag
Pro -7	-	expression tag
Arg -6	-	expression tag
Gly -5	-	expression tag
Ser -4	-	expression tag
His -3	-	expression tag
Met -2	-	expression tag
Ala -1	-	expression tag
Ser 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	8
	Total formula weight	389597.3
Non-Polymers*	Number of molecules	16
	Total formula weight	7445.3
All*	Total formula weight	397042.7

*Water molecules are not included.