7R39

Crystal structure of S-adenosyl-L-homocysteine hydrolase from Sulfolobus acidocaldarius in complex with adenosine

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004013	molecular_function	adenosylhomocysteinase activity
A	0005737	cellular_component	cytoplasm
A	0006730	biological_process	one-carbon metabolic process
A	0016787	molecular_function	hydrolase activity
A	0071269	biological_process	L-homocysteine biosynthetic process
B	0004013	molecular_function	adenosylhomocysteinase activity
B	0005737	cellular_component	cytoplasm
B	0006730	biological_process	one-carbon metabolic process
B	0016787	molecular_function	hydrolase activity
B	0071269	biological_process	L-homocysteine biosynthetic process
C	0004013	molecular_function	adenosylhomocysteinase activity
C	0005737	cellular_component	cytoplasm
C	0006730	biological_process	one-carbon metabolic process
C	0016787	molecular_function	hydrolase activity
C	0071269	biological_process	L-homocysteine biosynthetic process
D	0004013	molecular_function	adenosylhomocysteinase activity
D	0005737	cellular_component	cytoplasm
D	0006730	biological_process	one-carbon metabolic process
D	0016787	molecular_function	hydrolase activity
D	0071269	biological_process	L-homocysteine biosynthetic process
E	0004013	molecular_function	adenosylhomocysteinase activity
E	0005737	cellular_component	cytoplasm
E	0006730	biological_process	one-carbon metabolic process
E	0016787	molecular_function	hydrolase activity
E	0071269	biological_process	L-homocysteine biosynthetic process
F	0004013	molecular_function	adenosylhomocysteinase activity
F	0005737	cellular_component	cytoplasm
F	0006730	biological_process	one-carbon metabolic process
F	0016787	molecular_function	hydrolase activity
F	0071269	biological_process	L-homocysteine biosynthetic process
G	0004013	molecular_function	adenosylhomocysteinase activity
G	0005737	cellular_component	cytoplasm
G	0006730	biological_process	one-carbon metabolic process
G	0016787	molecular_function	hydrolase activity
G	0071269	biological_process	L-homocysteine biosynthetic process
H	0004013	molecular_function	adenosylhomocysteinase activity
H	0005737	cellular_component	cytoplasm
H	0006730	biological_process	one-carbon metabolic process
H	0016787	molecular_function	hydrolase activity
H	0071269	biological_process	L-homocysteine biosynthetic process

Functional Information from PROSITE/UniProt

site_id	PS00738
Number of Residues	15
Details	ADOHCYASE_1 S-adenosyl-L-homocysteine hydrolase signature 1. GSNpLSTQDdVAAGL

Chain	Residue	Details
A	GLY74-LEU88

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site_id	PS00739
Number of Residues	18
Details	ADOHCYASE_2 S-adenosyl-L-homocysteine hydrolase signature 2. GKvavViGYGwVGRGiaS

Chain	Residue	Details
A	GLY204-SER221

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	96
Details	BINDING: BINDING => ECO:0000255|HAMAP-Rule:MF_00563

Chain	Residue	Details
A	THR53
A	ASN269
A	SER290
A	ASN337
B	THR53
B	ASP124
B	GLU147
B	THR148
B	LYS177
B	ASP181
B	ASN182
A	ASP124
B	GLY211
B	GLU234
B	ASN269
B	SER290
B	ASN337
C	THR53
C	ASP124
C	GLU147
C	THR148
C	LYS177
A	GLU147
C	ASP181
C	ASN182
C	GLY211
C	GLU234
C	ASN269
C	SER290
C	ASN337
D	THR53
D	ASP124
D	GLU147
A	THR148
D	THR148
D	LYS177
D	ASP181
D	ASN182
D	GLY211
D	GLU234
D	ASN269
D	SER290
D	ASN337
E	THR53
A	LYS177
E	ASP124
E	GLU147
E	THR148
E	LYS177
E	ASP181
E	ASN182
E	GLY211
E	GLU234
E	ASN269
E	SER290
A	ASP181
E	ASN337
F	THR53
F	ASP124
F	GLU147
F	THR148
F	LYS177
F	ASP181
F	ASN182
F	GLY211
F	GLU234
A	ASN182
F	ASN269
F	SER290
F	ASN337
G	THR53
G	ASP124
G	GLU147
G	THR148
G	LYS177
G	ASP181
G	ASN182
A	GLY211
G	GLY211
G	GLU234
G	ASN269
G	SER290
G	ASN337
H	THR53
H	ASP124
H	GLU147
H	THR148
H	LYS177
A	GLU234
H	ASP181
H	ASN182
H	GLY211
H	GLU234
H	ASN269
H	SER290
H	ASN337

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