7QU1

Machupo virus GP1 glycoprotein in complex with Fab fragment of antibody MAC1

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Fab MAC1 heavy chain	polymer	234	25234.1	1		Mus musculus
2	B (B)	Fab MAC1 light chain	polymer	217	24090.6	1		Mus musculus
3	C (C)	Pre-glycoprotein polyprotein GP complex	polymer	182	21050.9	1	UniProt (Q6PXP4) Pfam (PF00798)	Machupo mammarenavirus	Pre-GP-C
4	D (D)	alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		1559.4	1	In PDB GlyTouCan (G83161QT)
5	E, F, G, H, I... (A, B)	GLYCEROL	non-polymer		92.1	10	Chemie (GOL)
6	O, P, Q (C)	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	3	Chemie (NAG)
7	R, S, T (A, B, C)	water	water		18.0	358	Chemie (HOH)

Sequence modifications

C: 87 - 257 (UniProt: Q6PXP4)

PDB	External Database	Details
Gly 258	-	expression tag
Thr 259	-	expression tag
Gly 260	-	expression tag
Thr 261	-	expression tag
Lys 262	-	expression tag
His 263	-	expression tag
His 264	-	expression tag
His 265	-	expression tag
His 266	-	expression tag
His 267	-	expression tag
His 268	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	3
	Total formula weight	70375.6
Branched	Number of molecules	1
	Total formula weight	1559.4
Non-Polymers*	Number of molecules	13
	Total formula weight	1584.6
All*	Total formula weight	73519.5

*Water molecules are not included.