7QTX
Kaposi sarcoma associated herpes virus (KSHV) encoded apoptosis inhibitor, KsBcl-2 in complex with Puma BH3
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Bcl-2 | polymer | 151 | 16637.2 | 1 | UniProt (Q76RI8) Pfam (PF00452) | Human gammaherpesvirus 8 | ORF 16,ORF16,ORF16 protein |
| 2 | B (B) | Bcl-2-binding component 3, isoforms 1/2 | polymer | 26 | 3210.5 | 1 | UniProt (Q9BXH1) | Homo sapiens | JFY-1,p53 up-regulated modulator of apoptosis |
| 3 | C, D, E (A) | BROMIDE ION | non-polymer | 79.9 | 3 | Chemie (BR) | |||
| 4 | F, G, H (A, B) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 3 | Chemie (EDO) | |||
| 5 | I, J (A, B) | water | water | 18.0 | 95 | Chemie (HOH) |
Sequence modifications
A: 1 - 146 (UniProt: Q76RI8)
| PDB | External Database | Details |
|---|---|---|
| Gly -4 | - | expression tag |
| Pro -3 | - | expression tag |
| Leu -2 | - | expression tag |
| Gly -1 | - | expression tag |
| Ser 0 | - | expression tag |
| Ala 117 | Val 117 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 19847.7 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 425.9 | |
| All* | Total formula weight | 20273.6 |
