7QTI
SARS-CoV-2 S Omicron Spike B.1.1.529 - 3-P2G3 and 1-P5C3 Fabs (Global)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C, G (G, B, I) | P2G3 Heavy Chain | polymer | 228 | 24562.5 | 3 | Homo sapiens | ||
| 2 | B, D, H (H, C, J) | P2G3 Light Chain | polymer | 214 | 23321.8 | 3 | Homo sapiens | ||
| 3 | E (E) | P5C3 Light Chain | polymer | 215 | 23388.9 | 1 | Homo sapiens | ||
| 4 | F (F) | P5C3 Heavy Chain | polymer | 221 | 23362.1 | 1 | Homo sapiens | ||
| 5 | I, J, K (D, K, A) | Spike glycoprotein,Envelope glycoprotein | polymer | 1285 | 142558.1 | 3 | UniProt (P0DTC2) UniProt (M1E1E4) Pfam (PF16451) Pfam (PF09408) Pfam (PF19209) Pfam (PF01601) Pfam (PF07921) | Severe acute respiratory syndrome coronavirus 2 | S glycoprotein,E2,Peplomer protein |
| 6 | L, M, N, O, P... (L, M, N, O, P...) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 14 | In PDB GlyTouCan (G42666HT) | |||
| 7 | X (X) | alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 748.7 | 1 | In PDB GlyTouCan (G81315DD) | |||
| 8 | AA, BA (a, b) | beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 586.5 | 2 | In PDB GlyTouCan (G15407YE) | |||
| 9 | AB, BB, CA, DA, EA... (A, D, K) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 26 | Chemie (NAG) |
Sequence modifications
D, K, A: 1 - 1202 (UniProt: P0DTC2)
D, K, A: 1208 - 1237 (UniProt: M1E1E4)
| PDB | External Database | Details |
|---|---|---|
| Val 67 | Ala 67 | conflict |
| - | His 69 | deletion |
| - | Val 70 | deletion |
| Ile 93 | Thr 95 | conflict |
| - | Gly 142 | deletion |
| - | Val 143 | deletion |
| - | Tyr 144 | deletion |
| Asp 140 | Tyr 145 | conflict |
| Ile 206 | - | insertion |
| Val 207 | - | insertion |
| Arg 208 | Asn 211 | conflict |
| Glu 209 | Leu 212 | conflict |
| Pro 210 | Val 213 | conflict |
| Glu 211 | Arg 214 | conflict |
| Asp 336 | Gly 339 | conflict |
| Leu 368 | Ser 371 | conflict |
| Pro 370 | Ser 373 | conflict |
| Phe 372 | Ser 375 | conflict |
| Asn 414 | Lys 417 | conflict |
| Lys 437 | Asn 440 | conflict |
| Ser 443 | Gly 446 | conflict |
| Asn 474 | Ser 477 | conflict |
| Lys 475 | Thr 478 | conflict |
| Ala 481 | Glu 484 | conflict |
| Arg 490 | Gln 493 | conflict |
| Ser 493 | Gly 496 | conflict |
| Arg 495 | Gln 498 | conflict |
| Tyr 498 | Asn 501 | conflict |
| His 502 | Tyr 505 | conflict |
| Lys 544 | Thr 547 | conflict |
| Gly 611 | Asp 614 | conflict |
| Tyr 652 | His 655 | conflict |
| Lys 676 | Asn 679 | conflict |
| His 678 | Pro 681 | conflict |
| Gly 679 | Arg 682 | conflict |
| Ser 680 | Arg 683 | conflict |
| Ser 682 | Arg 685 | conflict |
| Lys 761 | Asn 764 | conflict |
| Tyr 793 | Asp 796 | conflict |
| Lys 853 | Asn 856 | conflict |
| His 951 | Gln 954 | conflict |
| Lys 966 | Asn 969 | conflict |
| Phe 978 | Leu 981 | conflict |
| Pro 983 | Lys 986 | conflict |
| Pro 984 | Val 987 | conflict |
| Tyr 1203 | - | linker |
| Glu 1204 | - | linker |
| Gln 1205 | - | linker |
| Gly 1206 | - | linker |
| Ser 1207 | - | linker |
| PDB | External Database | Details |
|---|---|---|
| Arg 1236 | Ser 29 | conflict |
| Leu 1238 | - | expression tag |
| Glu 1239 | - | expression tag |
| Val 1240 | - | expression tag |
| Leu 1241 | - | expression tag |
| Phe 1242 | - | expression tag |
| Gln 1243 | - | expression tag |
| Gly 1244 | - | expression tag |
| Pro 1245 | - | expression tag |
| Gly 1246 | - | expression tag |
| His 1247 | - | expression tag |
| His 1248 | - | expression tag |
| His 1249 | - | expression tag |
| His 1250 | - | expression tag |
| His 1251 | - | expression tag |
| His 1252 | - | expression tag |
| His 1253 | - | expression tag |
| His 1254 | - | expression tag |
| Ser 1255 | - | expression tag |
| Ala 1256 | - | expression tag |
| Trp 1257 | - | expression tag |
| Ser 1258 | - | expression tag |
| His 1259 | - | expression tag |
| Pro 1260 | - | expression tag |
| Gln 1261 | - | expression tag |
| Phe 1262 | - | expression tag |
| Glu 1263 | - | expression tag |
| Lys 1264 | - | expression tag |
| Gly 1265 | - | expression tag |
| Gly 1266 | - | expression tag |
| Gly 1267 | - | expression tag |
| Ser 1268 | - | expression tag |
| Gly 1269 | - | expression tag |
| Gly 1270 | - | expression tag |
| Gly 1271 | - | expression tag |
| Gly 1272 | - | expression tag |
| Ser 1273 | - | expression tag |
| Gly 1274 | - | expression tag |
| Gly 1275 | - | expression tag |
| Ser 1276 | - | expression tag |
| Ala 1277 | - | expression tag |
| Trp 1278 | - | expression tag |
| Ser 1279 | - | expression tag |
| His 1280 | - | expression tag |
| Pro 1281 | - | expression tag |
| Gln 1282 | - | expression tag |
| Phe 1283 | - | expression tag |
| Glu 1284 | - | expression tag |
| Lys 1285 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 11 |
| Total formula weight | 618078.0 | |
| Branched | Number of molecules | 17 |
| Total formula weight | 7863.4 | |
| Non-Polymers* | Number of molecules | 26 |
| Total formula weight | 5751.4 | |
| All* | Total formula weight | 631692.8 |
