7QSC

GTPase IN COMPLEX WITH GDP.MGF3-

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, C	Rho GTPase-activating protein 1	polymer	244	27502.5	2	UniProt (Q07960) Pfam (PF00620) In PDB	Homo sapiens (human)	CDC42 GTPase-activating protein,GTPase-activating protein rhoGAP,Rho-related small GTPase protein activator,Rho-type GTPase-activating protein 1,p50-RhoGAP
2	B, D	Transforming protein RhoA	polymer	192	21688.9	2	UniProt (P61586) Pfam (PF00071) In PDB	Homo sapiens (human)	Rho cDNA clone 12,h12
3	B, D	GUANOSINE-5'-DIPHOSPHATE	non-polymer		443.2	2	Chemie (GDP)
4	B, D	TRIFLUOROMAGNESATE	non-polymer		81.3	2	Chemie (MGF)
5	B, D	MAGNESIUM ION	non-polymer		24.3	2	Chemie (MG)
6		water	water		18.0	313	Chemie (HOH)

Sequence modifications

A, C: 1 - 242 (UniProt: Q07960)

PDB	External Database	Details
Gly -1	-	expression tag
Ser 0	-	expression tag
Ala 85	Arg 282	engineered mutation

B, D: 2 - 193 (UniProt: P61586)

PDB	External Database	Details
Asn 25	Phe 25	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	98382.7
Non-Polymers*	Number of molecules	6
	Total formula weight	1097.6
All*	Total formula weight	99480.3

*Water molecules are not included.