7QQ5
Structure of CTX-M-15 K73A mutant crystallised in the presence of enmetazobactam (AAI101)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Beta-lactamase | polymer | 265 | 28234.9 | 1 | UniProt (W1EPV7) In PDB | Klebsiella pneumoniae IS53 | |
| 2 | A | SULFATE ION | non-polymer | 96.1 | 4 | Chemie (SO4) | |||
| 3 | A | CHLORIDE ION | non-polymer | 35.5 | 1 | Chemie (CL) | |||
| 4 | water | water | 18.0 | 335 | Chemie (HOH) |
Sequence modifications
A: 26 - 288 (UniProt: W1EPV7)
| PDB | External Database | Details |
|---|---|---|
| Gly 24 | - | expression tag |
| Pro 25 | - | expression tag |
| Dsn 70 | Ser 73 | conflict |
| Ala 73 | Lys 76 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 28234.9 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 419.7 | |
| All* | Total formula weight | 28654.6 |
