7QPP
High resolution structure of human VDR ligand binding domain in complex with calcitriol
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Vitamin D3 receptor | polymer | 263 | 29805.3 | 1 | UniProt (P11473) Pfam (PF00104) | Homo sapiens (human) | VDR,1,25-dihydroxyvitamin D3 receptor,Nuclear receptor subfamily 1 group I member 1 |
| 2 | B (A) | 5-{2-[1-(5-HYDROXY-1,5-DIMETHYL-HEXYL)-7A-METHYL-OCTAHYDRO-INDEN-4-YLIDENE]-ETHYLIDENE}-4-METHYLENE-CYCLOHEXANE-1,3-DIOL | non-polymer | 416.6 | 1 | Chemie (VDX) | |||
| 3 | C (A) | SULFATE ION | non-polymer | 96.1 | 1 | Chemie (SO4) | |||
| 4 | D (A) | water | water | 18.0 | 410 | Chemie (HOH) |
Sequence modifications
A: 118 - 216 (UniProt: P11473)
A: 217 - 427 (UniProt: P11473)
| PDB | External Database | Details |
|---|---|---|
| Gly 114 | - | expression tag |
| Ser 115 | - | expression tag |
| His 116 | - | expression tag |
| Met 117 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 29805.3 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 512.7 | |
| All* | Total formula weight | 30318.0 |
