7QPP

High resolution structure of human VDR ligand binding domain in complex with calcitriol

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Vitamin D3 receptor	polymer	263	29805.3	1	UniProt (P11473) Pfam (PF00104)	Homo sapiens (human)	VDR,1,25-dihydroxyvitamin D3 receptor,Nuclear receptor subfamily 1 group I member 1
2	B (A)	5-{2-[1-(5-HYDROXY-1,5-DIMETHYL-HEXYL)-7A-METHYL-OCTAHYDRO-INDEN-4-YLIDENE]-ETHYLIDENE}-4-METHYLENE-CYCLOHEXANE-1,3-DIOL	non-polymer		416.6	1	Chemie (VDX) PubChem (21158442) PubChem (22811021) PubChem (25056915) PubChem (25144925) PubChem (176541417) PubChem (177626446) PubChem (16759357) PubChem (25244372) PubChem (46780152) PubChem (53846427) PubChem (57358782) PubChem (57824615) PubChem (44348524) PubChem (44445686) PubChem (71434160) PubChem (71776638) PubChem (87065662) PubChem (90690610) PubChem (91507903) PubChem (91884833) PubChem (5280453) PubChem (5283737) PubChem (95566291) PubChem (98043898) PubChem (98043896) PubChem (50990009) PubChem (118719297) PubChem (6439628) PubChem (53675483) PubChem (124554638) PubChem (9844833) PubChem (9953732) PubChem (53846420) PubChem (53846421) PubChem (53846422) PubChem (53846423) PubChem (53846424) PubChem (53846425) PubChem (53846429) PubChem (53846432) PubChem (53846434) PubChem (53846435) PubChem (133655777) PubChem (56675037) PubChem (57069375) PubChem (12096001) PubChem (12095999) PubChem (13019064) PubChem (142186967) PubChem (142965989) PubChem (57853710) PubChem (59072033) PubChem (59824443) PubChem (59966627) PubChem (59966628) PubChem (59966641) PubChem (59966648) PubChem (59966656) PubChem (60120675) PubChem (71296883) PubChem (71586635) PubChem (71699993) PubChem (73707427) PubChem (73946427) PubChem (87060437) PubChem (88093945) PubChem (88093948) PubChem (88205154) PubChem (89082395) PubChem (89187208) PubChem (89735852) PubChem (90909703) PubChem (90942134) PubChem (90997437) PubChem (91170688) PubChem (91172822) PubChem (91400094) PubChem (91442807) PubChem (91543944) PubChem (91884755) PubChem (92974077) PubChem (95566292) PubChem (98043897) PubChem (98043899) PubChem (98116576) PubChem (98621118) PubChem (101088599) PubChem (101099404) PubChem (102426204) PubChem (102552746) PubChem (117828099) PubChem (118855589) PubChem (2524) PubChem (122451302) PubChem (36083) PubChem (123249588) PubChem (134070) PubChem (124220088) PubChem (124584674) PubChem (124604783) PubChem (5283736) PubChem (5283739) PubChem (5283740) PubChem (5283741) PubChem (5283742) PubChem (5353466) PubChem (5371993) PubChem (125032907) PubChem (6376279) PubChem (6434112) PubChem (6437079) PubChem (129010338) PubChem (9802028) PubChem (9823224) PubChem (9866622) PubChem (9909846) PubChem (9963516) PubChem (10093379) PubChem (10180181) PubChem (10180182) PubChem (10873438) PubChem (11112510) PubChem (11292963) PubChem (129627816) PubChem (129631814) PubChem (12096000) PubChem (13019045) PubChem (13019047) PubChem (13019052) PubChem (13019062) PubChem (13019065) PubChem (13019066) PubChem (13019068) PubChem (13019072) PubChem (13019077) PubChem (131954609) PubChem (134693124) PubChem (134694664) PubChem (139024314) PubChem (154790143) PubChem (154831899) PubChem (156599239) PubChem (162489847) PubChem (162904206) PubChem (163285334) PubChem (164576789) PubChem (166640002) PubChem (171114678) PubChem (171157379) PubChem (172966559) PubChem (173519260)
3	C (A)	SULFATE ION	non-polymer		96.1	1	Chemie (SO4)
4	D (A)	water	water		18.0	410	Chemie (HOH)

Sequence modifications

A: 118 - 216 (UniProt: P11473)

PDB	External Database	Details
Gly 114	-	expression tag
Ser 115	-	expression tag
His 116	-	expression tag
Met 117	-	expression tag

A: 217 - 427 (UniProt: P11473)

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	29805.3
Non-Polymers*	Number of molecules	2
	Total formula weight	512.7
All*	Total formula weight	30318.0

*Water molecules are not included.