7QPP

High resolution structure of human VDR ligand binding domain in complex with calcitriol

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003677	molecular_function	DNA binding
A	0004879	molecular_function	nuclear receptor activity
A	0006355	biological_process	regulation of DNA-templated transcription

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	18
Details	Region: {"description":"Interaction with coactivator LXXLL motif","evidences":[{"source":"UniProtKB","id":"P13053","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	8
Details	Motif: {"description":"9aaTAD","evidences":[{"source":"PubMed","id":"30468856","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI3
Number of Residues	2
Details	Binding site: {"evidences":[{"source":"PubMed","id":"10678179","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"11344298","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1DB1","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1IE8","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI4
Number of Residues	1
Details	Binding site: {"evidences":[{"source":"PubMed","id":"10678179","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"11344298","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1DB1","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI5
Number of Residues	2
Details	Binding site: {"evidences":[{"source":"PubMed","id":"10678179","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"11344298","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1IE8","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI6
Number of Residues	1
Details	Binding site: {"evidences":[{"source":"PubMed","id":"10678179","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"11344298","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

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