7QPJ
Crystal structure of engineered TCR (756) complexed to HLA-A*02:01 presenting MAGE-A10 9-mer peptide
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | C | MHC class I antigen | polymer | 277 | 32082.5 | 1 | UniProt (Q861F7) Pfam (PF00129) Pfam (PF07654) UniProt (by SIFTS) (A0A140T913) In PDB | Homo sapiens (human) | |
2 | D | Beta-2-microglobulin | polymer | 100 | 11879.4 | 1 | UniProt (P61769) Pfam (PF07654) In PDB | Homo sapiens (human) | |
3 | E | Melanoma-associated antigen 10 | polymer | 9 | 1035.2 | 1 | UniProt (P43363) In PDB | Homo sapiens | Cancer/testis antigen 1.10,CT1.10,MAGE-10 antigen |
4 | A | T-cell receptor alpha chain | polymer | 206 | 22761.0 | 1 | Homo sapiens (Human) | ||
5 | B | T-cell receptor beta chain | polymer | 241 | 27163.4 | 1 | Homo sapiens (Human) | ||
6 | C | GLYCEROL | non-polymer | 92.1 | 4 | Chemie (GOL) | |||
7 | water | water | 18.0 | 528 | Chemie (HOH) |
Sequence modifications
C: 2 - 277 (UniProt: Q861F7)
D: 2 - 100 (UniProt: P61769)
PDB | External Database | Details |
---|---|---|
Met 1 | - | initiating methionine |
PDB | External Database | Details |
---|---|---|
Met 1 | - | initiating methionine |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 5 |
Total formula weight | 94921.4 | |
Non-Polymers* | Number of molecules | 4 |
Total formula weight | 368.4 | |
All* | Total formula weight | 95289.8 |