7QO1
complex of DNA ligase I and FEN1 on PCNA and DNA
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | DNA ligase 1 | polymer | 760 | 84248.6 | 1 | UniProt (P18858) Pfam (PF04675) Pfam (PF01068) Pfam (PF04679) | Homo sapiens (human) | DNA ligase I,Polydeoxyribonucleotide synthase [ATP] 1 |
| 2 | B, C, D (B, F, G) | Proliferating cell nuclear antigen | polymer | 264 | 29088.1 | 3 | UniProt (P12004) Pfam (PF00705) Pfam (PF02747) | Homo sapiens (human) | PCNA,Cyclin |
| 3 | E (H) | Oligo19ddC | polymer | 19 | 5802.7 | 1 | synthetic construct | ||
| 4 | F (I) | Oligo13P | polymer | 13 | 3976.6 | 1 | synthetic construct | ||
| 5 | G (J) | Oligo32 | polymer | 32 | 9845.3 | 1 | synthetic construct | ||
| 6 | H (Y) | Flap endonuclease 1 | polymer | 380 | 42617.0 | 1 | UniProt (P39748) Pfam (PF00752) Pfam (PF00867) | Homo sapiens (human) | FEN-1,DNase IV,Flap structure-specific endonuclease 1,Maturation factor 1,hFEN-1 |
| 7 | I (I) | ADENOSINE MONOPHOSPHATE | non-polymer | 347.2 | 1 | Chemie (AMP) PubChem (224) PubChem (34768) PubChem (83862) PubChem (446048) PubChem (515384) PubChem (638042) PubChem (5316444) PubChem (5742864) PubChem (12163610) PubChem (12358355) PubChem (16397049) PubChem (16760266) PubChem (40467049) PubChem (40469468) PubChem (44348067) PubChem (45358029) PubChem (46874558) PubChem (40459109) PubChem (46875232) PubChem (177678969) PubChem (6083) PubChem (1549371) PubChem (92144436) PubChem (57358045) PubChem (57879893) PubChem (57879902) PubChem (12358354) PubChem (122197642) PubChem (162290139) PubChem (162946266) PubChem (171699505) |
Sequence modifications
A: 161 - 919 (UniProt: P18858)
B, F, G: 1 - 261 (UniProt: P12004)
Y: 1 - 380 (UniProt: P39748)
| PDB | External Database | Details |
|---|---|---|
| Cys 160 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Gly -2 | - | expression tag |
| Pro -1 | - | expression tag |
| His 0 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Ala 181 | Asp 181 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 8 |
| Total formula weight | 233754.5 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 347.2 | |
| All* | Total formula weight | 234101.7 |
