7QO1
complex of DNA ligase I and FEN1 on PCNA and DNA
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | DNA ligase 1 | polymer | 760 | 84248.6 | 1 | UniProt (P18858) Pfam (PF04675) Pfam (PF01068) Pfam (PF04679) | Homo sapiens (human) | DNA ligase I,Polydeoxyribonucleotide synthase [ATP] 1 |
| 2 | B, C, D (B, F, G) | Proliferating cell nuclear antigen | polymer | 264 | 29088.1 | 3 | UniProt (P12004) Pfam (PF00705) Pfam (PF02747) | Homo sapiens (human) | PCNA,Cyclin |
| 3 | E (H) | Oligo19ddC | polymer | 19 | 5802.7 | 1 | synthetic construct | ||
| 4 | F (I) | Oligo13P | polymer | 13 | 3976.6 | 1 | synthetic construct | ||
| 5 | G (J) | Oligo32 | polymer | 32 | 9845.3 | 1 | synthetic construct | ||
| 6 | H (Y) | Flap endonuclease 1 | polymer | 380 | 42617.0 | 1 | UniProt (P39748) Pfam (PF00752) Pfam (PF00867) | Homo sapiens (human) | FEN-1,DNase IV,Flap structure-specific endonuclease 1,Maturation factor 1,hFEN-1 |
| 7 | I (I) | ADENOSINE MONOPHOSPHATE | non-polymer | 347.2 | 1 | Chemie (AMP) |
Sequence modifications
A: 161 - 919 (UniProt: P18858)
B, F, G: 1 - 261 (UniProt: P12004)
Y: 1 - 380 (UniProt: P39748)
| PDB | External Database | Details |
|---|---|---|
| Cys 160 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Gly -2 | - | expression tag |
| Pro -1 | - | expression tag |
| His 0 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Ala 181 | Asp 181 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 8 |
| Total formula weight | 233754.5 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 347.2 | |
| All* | Total formula weight | 234101.7 |
