7QM2

Crystal structure of the PP1/PTG/beta-cyclodextrin ternary complex

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, C (A, C)	Serine/threonine-protein phosphatase PP1-alpha catalytic subunit	polymer	299	34162.1	2	UniProt (P62136) Pfam (PF16891) Pfam (PF00149)	Homo sapiens (human)	PP-1A
2	B, D (B, D)	Protein phosphatase 1 regulatory subunit 3C	polymer	200	23039.7	2	UniProt (Q9UQK1) Pfam (PF03370)	Homo sapiens (human)	Protein phosphatase 1 regulatory subunit 5,PP1 subunit R5,Protein targeting to glycogen,PTG
3	E, F (E, F)	Cycloheptakis-(1-4)-(alpha-D-glucopyranose)	branched		1153.0	2	In PDB BIRD (PRD_900012) GlyTouCan (G01435GL)
4	G, H, I, J (A, B, C, D)	water	water		18.0	19	Chemie (HOH)

Sequence modifications

A, C: 7 - 300 (UniProt: P62136)

PDB	External Database	Details
Gly 2	-	expression tag
His 3	-	expression tag
Met 4	-	expression tag
Gly 5	-	expression tag
Ser 6	-	expression tag

B, D: 70 - 264 (UniProt: Q9UQK1)

PDB	External Database	Details
Gly 65	-	expression tag
Pro 66	-	expression tag
Leu 67	-	expression tag
Gly 68	-	expression tag
Ser 69	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	114403.8
Branched	Number of molecules	2
	Total formula weight	2306.0
All*	Total formula weight	116709.8

*Water molecules are not included.