7QFT
Crystal structure of KLK6 in complex with compound 16a
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | Kallikrein-6 | polymer | 223 | 24417.7 | 2 | UniProt (Q92876) Pfam (PF00089) In PDB | Homo sapiens (human) | Neurosin,Protease M,SP59,Serine protease 18,Serine protease 9,Zyme |
| 2 | C, D | KLK6 Activity-Based Probe (Ahx-DPhe-Cha-Dht-Arg-DPP) | polymer | 5 | 965.1 | 2 | synthetic construct | ||
| 3 | water | water | 18.0 | 440 | Chemie (HOH) |
Sequence modifications
A, B: 16 - 245 (UniProt: Q92876)
| PDB | External Database | Details |
|---|---|---|
| Gly 74 | Arg 78 | engineered mutation |
| Gln 76 | Arg 80 | engineered mutation |
| Gln 132 | Asn 134 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 50765.7 | |
| All* | Total formula weight | 50765.7 |
