7QF0

Crystal structure of the SARS-CoV-2 RBD in complex with the human antibody CV2.2325

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	Spike protein S1	polymer	206	23068.7	1	UniProt (P0DTC2) Pfam (PF09408) In PDB	Severe acute respiratory syndrome coronavirus 2
2	H	CV2.2325 heavy chain	polymer	229	24483.3	1		Homo sapiens (Human)
3	L	CV2.2325 light chain	polymer	214	23394.0	1		Homo sapiens (Human)
4	B	2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		424.4	1	In PDB GlyTouCan (G42666HT)
5	A	SODIUM ION	non-polymer		23.0	1	Chemie (NA)
6	H, L	CHLORIDE ION	non-polymer		35.5	3	Chemie (CL)
7		water	water		18.0	234	Chemie (HOH)

Sequence modifications

A: 331 - 528 (UniProt: P0DTC2)

PDB	External Database	Details
Phe 367	Val 367	variant
Gly 529	-	expression tag
Ser 530	-	expression tag
Gly 531	-	expression tag
Asp 532	-	expression tag
Asp 533	-	expression tag
Asp 534	-	expression tag
Asp 535	-	expression tag
Lys 536	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	3
	Total formula weight	70946.0
Branched	Number of molecules	1
	Total formula weight	424.4
Non-Polymers*	Number of molecules	4
	Total formula weight	129.3
All*	Total formula weight	71499.7

*Water molecules are not included.