7QEZ
Crystal structure of the SARS-CoV-2 RBD in complex with the ultrapotent antibody CV2.1169 and CR3022
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Spike protein S1 | polymer | 206 | 23068.7 | 1 | UniProt (P0DTC2) Pfam (PF09408) | Severe acute respiratory syndrome coronavirus 2 | |
| 2 | B (E) | CR3022 heavy chain | polymer | 229 | 24321.2 | 1 | Homo sapiens (Human) | ||
| 3 | C (F) | CR3022 light chain | polymer | 221 | 24377.0 | 1 | Homo sapiens (Human) | ||
| 4 | D (H) | CV2.1169 IgA heavy chain | polymer | 225 | 24165.1 | 1 | Homo sapiens (Human) | ||
| 5 | E (L) | CV2.1169 light chain | polymer | 215 | 23547.1 | 1 | Homo sapiens (Human) | ||
| 6 | F (A) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 1 | Chemie (NAG) | |||
| 7 | G (L) | SULFATE ION | non-polymer | 96.1 | 1 | Chemie (SO4) | |||
| 8 | H (A) | water | water | 18.0 | 1 | Chemie (HOH) |
Sequence modifications
A: 331 - 528 (UniProt: P0DTC2)
| PDB | External Database | Details |
|---|---|---|
| Phe 367 | Val 367 | variant |
| Gly 529 | - | expression tag |
| Ser 530 | - | expression tag |
| Gly 531 | - | expression tag |
| Asp 532 | - | expression tag |
| Asp 533 | - | expression tag |
| Asp 534 | - | expression tag |
| Asp 535 | - | expression tag |
| Lys 536 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 5 |
| Total formula weight | 119479.1 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 317.3 | |
| All* | Total formula weight | 119796.3 |
