7QEM

bacterial IMPDH chimera

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D (A, B, C, D)	Inosine-5'-monophosphate dehydrogenase	polymer	507	54030.6	4	UniProt (P0ADG7) UniProt (Q9HXM5) Pfam (PF00478) Pfam (PF00571)	Escherichia coli	IMP dehydrogenase,IMPD,IMPDH
2	E, F, G, H (A, B, C, D)	INOSINIC ACID	non-polymer		348.2	4	Chemie (IMP)
3	I, J, K (A, C, D)	water	water		18.0	17	Chemie (HOH)

Sequence modifications

A, B, C, D: 1 - 91 (UniProt: P0ADG7)

PDB	External Database	Details
Met -19	-	initiating methionine
Gly -18	-	expression tag
Ser -17	-	expression tag
Ser -16	-	expression tag
His -15	-	expression tag
His -14	-	expression tag
His -13	-	expression tag
His -12	-	expression tag
His -11	-	expression tag
His -10	-	expression tag
Ser -9	-	expression tag
Ser -8	-	expression tag
Gly -7	-	expression tag
Leu -6	-	expression tag
Val -5	-	expression tag
Pro -4	-	expression tag
Arg -3	-	expression tag
Gly -2	-	expression tag
Ser -1	-	expression tag
His 0	-	expression tag

A, B, C, D: 92 - 201 (UniProt: Q9HXM5)
A, B, C, D: 202 - 487 (UniProt: P0ADG7)

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	216122.5
Non-Polymers*	Number of molecules	4
	Total formula weight	1392.8
All*	Total formula weight	217515.3

*Water molecules are not included.