7QB2
Pim1 in complex with (E)-4-((6-amino-1-methyl-2-oxoindolin-3-ylidene)methyl)benzoic acid and Pimtide
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Serine/threonine-protein kinase pim-1 | polymer | 312 | 35583.4 | 1 | UniProt (P11309) Pfam (PF00069) In PDB | Homo sapiens (human) | |
| 2 | D | Pimtide | polymer | 14 | 1592.8 | 1 | synthetic construct | ||
| 3 | A | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
| 4 | A | 4-[(E)-(6-azanyl-1-methyl-2-oxidanylidene-indol-3-ylidene)methyl]benzoic acid | non-polymer | 294.3 | 1 | Chemie (A7X) | |||
| 5 | water | water | 18.0 | 87 | Chemie (HOH) |
Sequence modifications
A: 1 - 312 (UniProt: P11309)
| PDB | External Database | Details |
|---|---|---|
| Gly 250 | Arg 250 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 37176.2 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 386.4 | |
| All* | Total formula weight | 37562.6 |
