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7QAA

Crystal structure of RARalpha/RXRalpha ligand binding domain heterodimer in complex with BMS614 and oleic acid

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1ARetinoic acid receptor RXR-alphapolymer23326044.21UniProt (P28700)
Pfam (PF00104)
In PDB
Mus musculus (house mouse)Nuclear receptor subfamily 2 group B member 1,Retinoid X receptor alpha
2BIsoform Alpha-1-deltaBC of Retinoic acid receptor alphapolymer23526600.01UniProt (P10276)
Pfam (PF00104)
In PDB
Homo sapiens (human)RAR-alpha,Nuclear receptor subfamily 1 group B member 1
3AOLEIC ACIDnon-polymer282.51Chemie (OLA)
4B4-[(4,4-DIMETHYL-1,2,3,4-TETRAHYDRO-[1,2']BINAPTHALENYL-7-CARBONYL)-AMINO]-BENZOIC ACIDnon-polymer450.51Chemie (BMS)
5waterwater18.0121Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight52644.2
Non-Polymers*Number of molecules2
Total formula weight733.0
All*Total formula weight53377.2
*Water molecules are not included.

224004

PDB entries from 2024-08-21

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